There are 10 ways to get from Orlando to Florida Keys by plane, bus, shuttle, train, car, bus (Greyhound), or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Key West International Airport, bus
best- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
5h 29m$144–746Bus
cheapest- Take the bus from Orlando to Miami Airport Stationbus FlixBus 2411 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
11h 45m$52–96Bus, shuttle
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
10h 7m$207–290Train, bus
- Take the train from Orlando to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
12h 20m$83–176Drive 355.3 mi
- Drive from Orlando to Florida Keyscar 355.3 mi
7h 21m$65–94Fly Orlando to Miami International Airport, shuttle
- Fly from Orlando (MCO) to Miami International Airport (MIA)plane MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
7h 54m$754–1,286Fly Orlando Sanford to Key West International Airport, bus
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
4h 46m$173–407Bus to Tampa, fly to Key West International Airport
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
7h 41m$146–449Fly Orlando to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane MCO - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
8h 21m$434–856Bus via Pembroke Pines
- Take the bus from Orlando to Sheridan Tri-Rail Stationbus Orlando to Miami
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
10h 51m$58–89
Orlando to Florida Keys by bus, shuttle, and foot
Questions & Answers
The cheapest way to get from Orlando to Florida Keys is to bus which costs $50 - $100 and takes 11h 45m.
The fastest way to get from Orlando to Florida Keys is to fly and bus which takes 4h 46m and costs $170 - $410.
No, there is no direct bus from Orlando to Florida Keys. However, there are services departing from Orlando and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 10h 51m.
The distance between Orlando and Florida Keys is 309 miles. The road distance is 357.4 miles.
The best way to get from Orlando to Florida Keys without a car is to bus and shuttle which takes 10h 7m and costs $200 - $290.
It takes approximately 5h 29m to get from Orlando to Florida Keys, including transfers.
Orlando to Florida Keys bus services, operated by Jet Set Express, depart from Orlando station.
Orlando to Florida Keys bus services, operated by Jet Set Express, arrive at Sheridan Tri-Rail Station.
Yes, the driving distance between Orlando to Florida Keys is 357 miles. It takes approximately 7h 21m to drive from Orlando to Florida Keys.
There are 972+ hotels available in Florida Keys.
What companies run services between Orlando, FL, USA and Florida Keys, FL, USA?
You can take a bus from Orlando to Florida Keys via Sheridan Tri-Rail Station, Sheridan Street Station, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 10h 51m.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $30–230
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $35–280
Flights from Tampa to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $35–250
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Delray Beach Amtrak
- Ave. Duration
- 4h 14m
- Frequency
- Twice daily
- Estimated price
- $55–130
- Website
- Amtrak
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
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