There are 9 ways to get from Orlando to Florida Keys by plane, bus, shuttle, train, car, bus (Greyhound), or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Key West International Airport, bus
best- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
5h 29m$144–566Bus
cheapest- Take the bus from Orlando to Miami Airport Stationbus FlixBus 2411 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
11h 44m$61–96Bus, shuttle
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
10h 7m$210–263Train, bus
- Take the train from Orlando to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
12h 20m$149–232Drive 355.3 mi
- Drive from Orlando to Florida Keyscar 355.3 mi
7h 21m$65–94Fly Orlando Sanford to Key West International Airport, bus
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
4h 40m$173–427Fly Orlando to Miami International Airport, shuttle
- Fly from Orlando (MCO) to Miami International Airport (MIA)plane MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
7h 55m$754–1,286Bus to Tampa, fly to Key West International Airport
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
7h 41m$137–359Bus via Pembroke Pines
- Take the bus from Orlando to Sheridan Tri-Rail Stationbus Orlando to Miami
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
10h 51m$62–89
Orlando to Florida Keys by bus, shuttle, and foot
Comparing Your Travel Options
The cheapest way to get from Orlando to Florida Keys is to bus which costs $60 - $100 and takes 11h 44m.
The fastest way to get from Orlando to Florida Keys is to fly and bus which takes 4h 40m and costs $170 - $430.
No, there is no direct bus from Orlando to Florida Keys. However, there are services departing from Orlando and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 10h 51m.
The distance between Orlando and Florida Keys is 309 miles. The road distance is 357.4 miles.
The best way to get from Orlando to Florida Keys without a car is to bus and shuttle which takes 10h 7m and costs $210 - $270.
It takes approximately 5h 29m to get from Orlando to Florida Keys, including transfers.
Orlando to Florida Keys bus services, operated by Jet Set Express, depart from Orlando station.
Orlando to Florida Keys bus services, operated by Jet Set Express, arrive at Sheridan Tri-Rail Station.
Yes, the driving distance between Orlando to Florida Keys is 357 miles. It takes approximately 7h 21m to drive from Orlando to Florida Keys.
There are 965+ hotels available in Florida Keys.
What companies run services between Orlando, FL, USA and Florida Keys, FL, USA?
You can take a bus from Orlando to Florida Keys via Sheridan Tri-Rail Station, Sheridan Street Station, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 10h 51m.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 19m
- When
- Monday, Thursday, Sunday, Wednesday, Friday, and Saturday
- Estimated price
- $35–250
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $35–270
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $35–270
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 23m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $65–470
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $45–240
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Friday, Monday, Sunday, and Thursday
- Estimated price
- $35–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Delray Beach Amtrak
- Ave. Duration
- 4h 14m
- Frequency
- Twice daily
- Estimated price
- $120–190
- Website
- Amtrak
- Phone
- +1 800-874-7245
- [email protected]
- Website
- Tri Rail
Train from Delray Beach Station to Miami Airport Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- Tri Rail
- Weekend | Holiday
- $5
- Weekday
- $6–9
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Orlando - RedCoach Station, FL to Miami Airport
- Ave. Duration
- 4h 25m
- Frequency
- 4 times a day
- Estimated price
- $55–80
- Website
- RedCoach
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $15–23
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
Bus from Orlando to Miami Airport Station
- Ave. Duration
- 4h 20m
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
- Phone
- (+1) 407 649 4994
- [email protected]
- Website
- Jet Set Express
Bus from Orlando to Sheridan Tri-Rail Station
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–45
- Website
- Jet Set Express
- Schedules at
- Jet Set Express
- Book at
- Jet Set Express
- Adult
- $30–45
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide















