There are 10 ways to get from Orlando to Greeneville by plane, car, bus, train, taxi, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando Sanford to Mcghee Tyson Airport, drive
best- Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane SFB - TYS
- Drive from Mcghee Tyson Airport (TYS) to Greenevillecar
3h 42m$206–895Fly Orlando to Asheville Regional Airport, drive
cheapest- Fly from Orlando (MCO) to Asheville Regional Airport (AVL)plane MCO - AVL
- Drive from ART Station to Greenevillecar
5h 43m$68–358Bus, drive
- Take the bus from Orlando Bus Station to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
- Drive from Asheville, NC to Greenevillecar
17h 20m$117–212Train, bus, drive
- Take the train from Orlando to Carytrain
- Take the train from Cary to Greensborotrain
- Take the bus from Greensboro Bus Stop to Asheville, NCbus
- Drive from Asheville, NC to Greenevillecar
21h 35m$208–462Drive 633.4 mi
- Drive from Orlando to Greenevillecar 633.4 mi
10h 57m$116–167Fly Orlando to Tri-Cities Regional Tn/Va Airport, taxi
- Fly from Orlando (MCO) to Tri-Cities Regional Tn/Va Airport (TRI)plane MCO - TRI
- Take the taxi from Tri-Cities-Regional-Airport-TRI to Greenevilletaxi
4h 6m$162–492Fly Orlando to Mcghee Tyson Airport, drive
- Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane MCO - TYS
- Drive from Mcghee Tyson Airport (TYS) to Greenevillecar
4h 28m$147–824Fly Orlando Sanford to Tri-Cities Regional Tn/Va Airport, taxi
- Fly from Orlando Sanford (SFB) to Tri-Cities Regional Tn/Va Airport (TRI)plane SFB - TRI
- Take the taxi from Tri-Cities-Regional-Airport-TRI to Greenevilletaxi
3h 8m$221–573Fly Orlando Sanford to Asheville Regional Airport, drive
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from ART Station to Greenevillecar
4h 56m$127–439Bus, shuttle
- Take the bus from Orlando Bus Station to Charlotte Bus Stationbus
- Take the bus from Charlotte to Boonebus
- Take a shuttle bus from Boone to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Allen Gap, TN
18h 30m$348–409
Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Orlando to Greeneville is to drive which costs $110 - $170 and takes 10h 57m.
The fastest way to get from Orlando to Greeneville is to fly and taxi which takes 3h 8m and costs $220 - $600.
The distance between Orlando and Greeneville is 619 miles. The road distance is 637.1 miles.
The best way to get from Orlando to Greeneville without a car is to bus and shuttle which takes 18h 30m and costs $340 - $410.
It takes approximately 3h 42m to get from Orlando to Greeneville, including transfers.
Yes, the driving distance between Orlando to Greeneville is 637 miles. It takes approximately 10h 57m to drive from Orlando to Greeneville.
There are 22+ hotels available in Greeneville.
What companies run services between Orlando, FL, USA and Greeneville, TN, USA?
There is no direct connection from Orlando to Greeneville. However, you can take the taxi to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then drive to Greeneville. Alternatively, you can take a bus from Orlando Bus Station to Greeneville via Charlotte Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 17h 20m.
- Website
- allegiantair.com
Flights from Orlando Sanford to Mcghee Tyson Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $130–800
Flights from Orlando to Mcghee Tyson Airport
- Ave. Duration
- 1h 43m
- When
- Friday, Monday, and Wednesday
- Estimated price
- $130–800
Flights from Orlando Sanford to Tri-Cities Regional Tn/Va Airport
- Ave. Duration
- 1h 41m
- When
- Monday, Friday, Thursday, and Sunday
- Estimated price
- $60–370
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $55–350
Flights from Orlando to Asheville Regional Airport
- Ave. Duration
- 1h 36m
- When
- Monday and Friday
- Estimated price
- $55–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Cary
- Ave. Duration
- 13h 34m
- Frequency
- Once daily
- Estimated price
- $150–360
- Website
- Amtrak
Train from Cary to Greensboro
- Ave. Duration
- 1h 21m
- Frequency
- 5 times a day
- Estimated price
- $17–45
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Charlotte Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $75–120
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Charlotte Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $75–120
- Schedules at
- Flixbus USA
- Ave. Duration
- 52 min
- Estimated price
- $100–130
Kingsport Cabbie
- Phone
- +1-423-963-4760
Reliable Taxi
- Phone
- +1-423-426-6003
Kingsport Cabbie
- Phone
- +1-423-963-4760
Reliable Taxi
- Phone
- +1-423-426-6003
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide




