There are 10 ways to get from Orlando to Kirksville by plane, bus, train, train (Amtrak), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Kirksville Regional Airport
best- Fly from Orlando (MCO) to Kirksville Regional Airport (IRK)plane MCO - IRK
7h 1m$137–507Bus, train
- Take the bus from Orlando Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Galesburgbus
- Take the train from Galesburg Amtrak Station to La Plata Stationtrain
29h 30m$267–506Train (Amtrak)
- Take the train from Orlando to Chicago Union Stationtrain Floridian
- Take the train from Chicago Union Station to La Plata Stationtrain Southwest Chief
45h 4m$694–1,380Drive 1,193.7 mi
- Drive from Orlando to Kirksvillecar 1,193.7 mi
20h$218–315Fly Orlando to Kansas City, train
- Fly from Orlando (MCO) to Kansas City (MCI)plane MCO - MCI
- Take the train from Kansas City to La Plata Stationtrain
9h 39m$302–1,252Fly Orlando Sanford to The Eastern Iowa Airport, drive
- Fly from Orlando Sanford (SFB) to The Eastern Iowa Airport (CID)plane SFB - CID
- Drive from Cedar-Rapids-Airport-CID to Kirksvillecar
6h 51m$190–578Fly Orlando to Lambert–St. Louis International Airport, shuttle
- Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane MCO - STL
- Take a shuttle bus from St. Louis to Bowling Green, Mo
- Take a shuttle bus from Bowling Green, Mo to Columbia
- Take a shuttle bus from Columbia to Hy-Vee - Kirksville
10h 58m$196–393Fly Orlando to Chicago Midway International Airport, train
- Fly from Orlando (MCO) to Chicago Midway International Airport (MDW)plane MCO - MDW
- Take the train from Chicago Union Station to La Plata Stationtrain
11h 6m$347–755Fly Orlando Sanford to Columbia Regional Airport, shuttle
- Fly from Orlando Sanford (SFB) to Columbia Regional Airport (COU)plane SFB - COU
- Take a shuttle bus from Columbia to Hy-Vee - Kirksville
5h 59m$205–584Fly Orlando Sanford to Midamerica St. Louis Airport, train, shuttle
- Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane SFB - BLV
- Take the train from SHILOH-SCOTT station to NORTH HANLEY stationtrain
- Take a shuttle bus from St. Louis to Bowling Green, Mo
- Take a shuttle bus from Bowling Green, Mo to Columbia
- Take a shuttle bus from Columbia to Hy-Vee - Kirksville
11h 25m$178–543
Orlando (MCO) to Kirksville Regional Airport (IRK) flights
Questions & Answers
The cheapest way to get from Orlando to Kirksville is to fly and shuttle which costs $190 - $400 and takes 10h 58m.
The fastest way to get from Orlando to Kirksville is to fly and shuttle which takes 5h 59m and costs $200 - $600.
No, there is no direct train from Orlando to Kirksville station. However, there are services departing from Orlando and arriving at La Plata Station via Chicago Union Station. The journey, including transfers, takes approximately 45h 4m.
The distance between Orlando and Kirksville is 1059 miles. The road distance is 1200.7 miles.
The best way to get from Orlando to Kirksville without a car is to bus and train which takes 29h 30m and costs $260 - $550.
It takes approximately 7h 1m to get from Orlando to Kirksville, including transfers.
Orlando to Kirksville train services, operated by Amtrak, depart from Orlando station.
The best way to get from Orlando to Kirksville is to fly which takes 7h 1m and costs $130 - $550. Alternatively, you can train, which costs $650 - $1,400 and takes 45h 4m.
Kirksville is 1h behind Orlando. It is currently 12:46 PM in Orlando and 11:46 AM in Kirksville.
Orlando to Kirksville train services, operated by Amtrak, arrive at Chicago Union Station.
What companies run services between Orlando, FL, USA and Kirksville, MO, USA?
American Airlines and Corporate Flight Management Inc fly from Orlando (MCO) to Kirksville Regional Airport (IRK) twice daily. Alternatively, you can take a train from Orlando to Kirksville via Chicago Union Station and La Plata Station in around 45h 4m.
- Website
- southwest.com
Flights from Orlando to Kansas City
- Ave. Duration
- 2h 54m
- When
- Every day
- Estimated price
- $140–650
Flights from Orlando to Kansas City via Nashville
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $140–650
Flights from Orlando to Kansas City via Lambert–St. Louis International Airport
- Ave. Duration
- 4h 40m
- When
- Sunday
- Estimated price
- $140–700
Flights from Orlando to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 32m
- When
- Every day
- Estimated price
- $110–550
Flights from Orlando to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 25m
- When
- Monday to Wednesday
- Estimated price
- $110–550
Flights from Orlando to Chicago Midway International Airport
- Ave. Duration
- 2h 46m
- When
- Every day
- Estimated price
- $80–390
Flights from Orlando to Chicago Midway International Airport via Nashville
- Ave. Duration
- 4h 38m
- When
- Tuesday to Friday
- Estimated price
- $85–400
- Website
- delta.com
Flights from Orlando to Kansas City via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $140–650
Flights from Orlando to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $110–550
- Website
- allegiantair.com
Flights from Orlando Sanford to The Eastern Iowa Airport
- Ave. Duration
- 2h 52m
- When
- Monday and Friday
- Estimated price
- $100–460
Flights from Orlando Sanford to Columbia Regional Airport
- Ave. Duration
- 2h 39m
- When
- Friday
- Estimated price
- $90–440
Flights from Orlando Sanford to Midamerica St. Louis Airport
- Ave. Duration
- 2h 21m
- When
- Monday, Friday, Thursday, and Sunday
- Estimated price
- $80–420
- Website
- contouraviation.com
Flights from Orlando to Kirksville Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $100–460
Flights from Orlando to Kirksville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 55m
- When
- Monday, Tuesday, Thursday, Friday, and Saturday
- Estimated price
- $120–550
- Website
- flyfrontier.com
Flights from Orlando to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 29m
- When
- Every day
- Estimated price
- $180–320
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Galesburg Amtrak Station to La Plata Station
- Ave. Duration
- 2h 13m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Train from Orlando to Chicago Union Station
- Ave. Duration
- 38h 55m
- Frequency
- Once daily
- Estimated price
- $550–1,200
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to La Plata Station
- Ave. Duration
- 4h 52m
- Frequency
- Once daily
- Estimated price
- $95–200
- Website
- https://www.amtrak.com/home.html
Train from Kansas City to La Plata Station
- Ave. Duration
- 2h 3m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to La Plata Station
- Ave. Duration
- 4h 52m
- Frequency
- Once daily
- Estimated price
- $95–200
- Website
- https://www.amtrak.com/home.html
- Phone
- 314-982-1406
- [email protected]
- Website
- metrostlouis.org
Train from SHILOH-SCOTT station to NORTH HANLEY station
- Ave. Duration
- 1h 9m
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://www.metrostlouis.org
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 15m
- Frequency
- Every 4 hours
- Estimated price
- $70–120
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Orlando Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Indianapolis Union Station
- Ave. Duration
- 11h 50m
- Frequency
- 4 times a day
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Galesburg
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
- Phone
- +1-888-875-6287
- Website
- oatstransit.org
Shuttle from St. Louis to Bowling Green, Mo
- Ave. Duration
- 1h 15m
- Frequency
- Twice a week
- Estimated price
- $3–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from Bowling Green, Mo to Columbia
- Ave. Duration
- 1h 45m
- Frequency
- On demand
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from Columbia to Hy-Vee - Kirksville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from Columbia to Hy-Vee - Kirksville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from St. Louis to Bowling Green, Mo
- Ave. Duration
- 1h 15m
- Frequency
- Twice a week
- Estimated price
- $3–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from Bowling Green, Mo to Columbia
- Ave. Duration
- 1h 45m
- Frequency
- On demand
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from Columbia to Hy-Vee - Kirksville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Orlando to Kirksville is 1201 miles. It takes approximately 20h to drive from Orlando to Kirksville.
Book your Orlando to Kirksville train tickets online with Omio.
There are 10+ hotels available in Kirksville.











