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How to get fromOrlando to La Crosseby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Find Transport to La Crosse

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There are 8 ways to get from Orlando to La Crosse by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to La Crosse

    best
    1. Fly from Orlando (MCO) to La Crosse (LSE)plane plane MCO - LSE
    7h 12m
    $116–485

  2. Bus

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    31h 22m
    $243–418

  3. Train (Amtrak)

    1. Take the train from Orlando to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    44h 54m
    $1,087–1,677

  4. Drive  1,392.2 mi

    1. Drive from Orlando to La Crossecar car 1,392.2 mi
    23h 53m
    $238–344

  5. Fly Orlando Sanford to La Crosse

    1. Fly from Orlando Sanford (SFB) to La Crosse (LSE)plane plane SFB - LSE
    4h 7m
    $180–576

  6. Fly Orlando to Dane County Regional Airport-Truax Field, bus

    1. Fly from Orlando (MCO) to Dane County Regional Airport-Truax Field (MSN)plane plane MCO - MSN
    2. Take the bus from Madison to La Crossebus bus
    8h 56m
    $129–499

  7. Fly Orlando to Minneapolis–Saint Paul International Airport, train

    1. Fly from Orlando (MCO) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCO - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    9h 13m
    $224–605

  8. Fly Orlando to General Mitchell International Airport, train

    1. Fly from Orlando (MCO) to General Mitchell International Airport (MKE)plane plane MCO - MKE
    2. Take the train from Milwaukee to La Crosse Amtrak Stationtrain train
    9h 5m
    $514–1,286

Orlando to La Crosse by bus

Calendar7Weekly Buses
Duration31h 22mAverage Duration
Ticket$243Cheapest Price
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Comparing Your Travel Options

Map of how to get from Orlando to La Crosse.ExpandLaunch map view
  • Distance: 1,224.7 mi
  • Duration: 7h 12m

What companies run services between Orlando, FL, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Orlando (MCO) to La Crosse (LSE) every 4 hours. Alternatively, you can take a bus from Orlando Bus Station to La Crosse via Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 31h 22m.

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Want to know more about travelling around United States

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