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How to get fromOrlando to La Crosseby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

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There are 7 ways to get from Orlando to La Crosse by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to La Crosse

    best
    1. Fly from Orlando (MCO) to La Crosse (LSE)plane plane MCO - LSE
    6h 54m
    $141–425

  2. Bus

    1. Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    30h 3m
    $293–534

  3. Train (Amtrak)

    1. Take the train from Orlando to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    44h 54m
    $648–1,306

  4. Drive 1,392.2 mi

    1. Drive from Orlando to La Crossecar car 1,392.2 mi
    23h 53m
    $255–367

  5. Fly Orlando Sanford to La Crosse

    1. Fly from Orlando Sanford (SFB) to La Crosse (LSE)plane plane SFB - LSE
    4h 7m
    $180–576

  6. Fly Orlando to Minneapolis–Saint Paul International Airport, train

    1. Fly from Orlando (MCO) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCO - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    9h 9m
    $244–1,190

  7. Fly Orlando to General Mitchell International Airport, train

    1. Fly from Orlando (MCO) to General Mitchell International Airport (MKE)plane plane MCO - MKE
    2. Take the train from Milwaukee to La Crosse Amtrak Stationtrain train
    8h 53m
    $224–696

Orlando to La Crosse by train (Amtrak)

Calendar7Weekly Trains
Duration44h 54mAverage Duration
Ticket$648Cheapest Price
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Questions & Answers

Map of how to get from Orlando to La Crosse.ExpandLaunch map view
  • Distance: 1,224.7 mi
  • Duration: 6h 54m

What companies run services between Orlando, FL, USA and La Crosse, WI, USA?

American Airlines, Frontier Airlines, and United Airlines fly from Orlando (MCO) to La Crosse (LSE) 5 times a day. Alternatively, you can take a bus from Orlando RedCoach Station to La Crosse via Atlanta - Civic Center MARTA Station, Civic Center Station, Garnett Station, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 30h 3m.

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