There are 3 ways to get from Orlando to Lake City by bus (Greyhound), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Orlando Bus Station to Lake City Bus Stationbus FlixBus 2451
3h 20m$24–50Drive 153.3 mi
- Drive from Orlando to Lake Citycar 153.3 mi
2h 30m$28–41Bus via Gainesville
- Take the bus from Orlando Bus Station to Gainesvillebus FlixBus 2415 / ...
- Take the bus from Gainesville to Lake City Bus Stationbus FlixBus 2451
4h 5m
Orlando to Lake City by bus
Questions & Answers
The cheapest way to get from Orlando to Lake City is to bus which costs $24 - $50 and takes 3h 20m.
The fastest way to get from Orlando to Lake City is to drive which takes 2h 30m and costs $28 - $45.
Yes, there is a direct bus departing from Orlando Bus Station station and arriving at Lake City Bus Station station. Services depart once daily, and operate every day. The journey takes approximately 3h 20m.
The distance between Orlando and Lake City is 158 miles. The road distance is 154.2 miles.
The best way to get from Orlando to Lake City without a car is to bus which takes 3h 20m and costs $24 - $50.
The bus from Orlando Bus Station to Lake City Bus Station takes 3h 20m including transfers and departs once daily.
Orlando to Lake City bus services, operated by FlixBus-us, depart from Orlando Bus Station.
Orlando to Lake City bus services, operated by FlixBus-us, arrive at Lake City Bus Station.
Yes, the driving distance between Orlando to Lake City is 154 miles. It takes approximately 2h 30m to drive from Orlando to Lake City.
Book your Orlando to Lake City bus tickets online with Omio and FlixBus.
What companies run services between Orlando, FL, USA and Lake City, FL, USA?
FlixBus-us operates a bus from Orlando Bus Station to Lake City Bus Station once daily, and the journey takes 3h 20m. Two other operators also service this route.
- Website
- flixbus.com
Bus from Orlando Bus Station to Lake City Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Gainesville
- Ave. Duration
- 2h 5m
- Frequency
- 5 times a day
- Schedules at
- flixbus.com
Bus from Gainesville to Lake City Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Schedules at
- flixbus.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Lake City Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Orlando Bus Station to Lake City Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $24–50
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando Bus Station to Gainesville
- Ave. Duration
- 1h 55m
- Frequency
- 4 times a day
- Estimated price
- $17–29
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 25+ hotels available in Lake City.