There are 5 ways to get from Orlando to Lake City by plane, car, bus, taxi, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Orlando, drive
best- Fly from Orlando (MCO) to Myrtle Beach (MYR)plane MCO - MYR
- Drive from Myrtle Beach (MYR) to Lake Citycar
4h 13m$103–338Drive 437.8 mi
cheapest- Drive from Orlando to Lake Citycar 437.8 mi
7h 17m$80–116Bus, taxi
- Take the bus from Orlando Bus Station to Florencebus FlixBus N2472
- Take the taxi from Florence to Lake Citytaxi
9h 3m$153–220Train (Amtrak)
- Take the train from Orlando to Kingstree Stationtrain Silver Meteor
9h 11m$190–358Bus to Tampa, fly, drive
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
- Drive from Myrtle Beach (MYR) to Lake Citycar
6h 39m$101–303
Orlando (MCO) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Orlando to Lake City is to drive which costs $80 - $120 and takes 7h 17m.
The fastest way to get from Orlando to Lake City is to fly and drive which takes 4h 13m and costs $100 - $340.
No, there is no direct train from Orlando to Lake City station. However, there are services departing from Orlando and arriving at Kingstree Station via . The journey, including transfers, takes approximately 9h 11m.
The distance between Orlando and Lake City is 469 miles. The road distance is 440.3 miles.
The best way to get from Orlando to Lake City without a car is to bus and taxi which takes 9h 3m and costs $150 - $220.
It takes approximately 4h 13m to get from Orlando to Lake City, including transfers.
Orlando to Lake City train services, operated by Amtrak, depart from Orlando station.
Orlando to Lake City train services, operated by Amtrak, arrive at Kingstree Station.
Yes, the driving distance between Orlando to Lake City is 440 miles. It takes approximately 7h 17m to drive from Orlando to Lake City.
There are five+ hotels available in Lake City.
What companies run services between Orlando, FL, USA and Lake City, SC, USA?
Amtrak operates a train from Orlando to Kingstree Station once daily. Tickets cost $140–300 and the journey takes 8h 49m.
- Website
- aa.com
Flights from Orlando to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $55–300
Flights from Tampa to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $65–350
- Website
- delta.com
Flights from Orlando to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–310
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $70–360
- Website
- flybreeze.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–280
Flights from Tampa to Myrtle Beach
- Ave. Duration
- 1h 41m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Kingstree Station
- Ave. Duration
- 8h 49m
- Frequency
- Once daily
- Estimated price
- $140–300
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Florence
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $13–22
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- $12–24
- Website
- Greyhound
Want to know more about travelling around United States
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