What is the cheapest way to get from Orlando to Mayo Clinic Florida?

The cheapest way to get from Orlando to Mayo Clinic Florida is to drive which costs $25 - $40 and takes 2h 19m.

What is the fastest way to get from Orlando to Mayo Clinic Florida?

The fastest way to get from Orlando to Mayo Clinic Florida is to drive which takes 2h 19m and costs $25 - $40.

Is there a direct bus between Orlando and Mayo Clinic Florida?

No, there is no direct bus from Orlando station to Mayo Clinic Florida. However, there are services departing from Orlando Bus Station and arriving at Beach Blvd + Hodges Blvd via JRTC Bay M. The journey, including transfers, takes approximately 3h 58m.

Is there a direct train between Orlando and Mayo Clinic Florida?

No, there is no direct train from Orlando to Mayo Clinic Florida. However, there are services departing from Orlando and arriving at Jacksonville via . The journey, including transfers, takes approximately 3h 48m.

How far is it from Orlando to Mayo Clinic Florida?

The distance between Orlando and Mayo Clinic Florida is 170 miles. The road distance is 137.9 miles.

How do I travel from Orlando to Mayo Clinic Florida without a car?

The best way to get from Orlando to Mayo Clinic Florida without a car is to train which takes 3h 48m and costs $100 - $170.

How long does it take to get from Orlando to Mayo Clinic Florida?

It takes approximately 3h 48m to get from Orlando to Mayo Clinic Florida, including transfers.

Where do I catch the Orlando to Mayo Clinic Florida bus from?

Orlando to Mayo Clinic Florida bus services, operated by Flixbus USA, depart from Orlando Bus Station.

Where do I catch the Orlando to Mayo Clinic Florida train from?

Orlando to Mayo Clinic Florida train services, operated by Amtrak, depart from Orlando station.

Train or bus from Orlando to Mayo Clinic Florida?

The best way to get from Orlando to Mayo Clinic Florida is to train which takes 3h 48m and costs $100 - $170. Alternatively, you can bus, which costs $30 - $55 and takes 3h 58m.

Where does the Orlando to Mayo Clinic Florida bus arrive?

Orlando to Mayo Clinic Florida bus services, operated by Flixbus USA, arrive at Jacksonville station.

Where does the Orlando to Mayo Clinic Florida train arrive?

Orlando to Mayo Clinic Florida train services, operated by Amtrak, arrive at Jacksonville station.

Can I drive from Orlando to Mayo Clinic Florida?

Yes, the driving distance between Orlando to Mayo Clinic Florida is 138 miles. It takes approximately 2h 19m to drive from Orlando to Mayo Clinic Florida.

Where can I stay near Mayo Clinic Florida?

There are 630+ hotels available in Mayo Clinic Florida.

Orlando to Mayo Clinic Florida - 3 ways to travel via train, bus, and car

How to get fromOrlando to Mayo Clinic Florida

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There are 3 ways to get from Orlando to Mayo Clinic Florida by train (Amtrak), bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train (Amtrak)
best
1. Take the train from Orlando to Jacksonvilletrain Silver Meteor / ...
3h 48m
$102–167
Drive 137.1 mi
cheapest
1. Drive from Orlando to Mayo Clinic Floridacar 137.1 mi
2h 19m
$25–37
Bus
1. Take the bus from Orlando Bus Station to Jacksonvillebus FlixBus 2433 / ...
2. Take the bus from JRTC Bay M to Beach Blvd + Hodges Blvdbus Fcf / ...
3h 58m
$33–51

Questions & Answers

Map of how to get from Orlando to Mayo Clinic Florida.

Launch map view

Distance: 169.3 mi
Duration: 3h 48m

What companies run services between Orlando, FL, USA and Mayo Clinic Florida, FL, USA?

Amtrak operates a train from Orlando to Jacksonville twice daily. Tickets cost $45–100 and the journey takes 3h 15m. Alternatively, you can take a bus from Orlando Bus Station to Mayo Clinic Florida via Jacksonville, JRTC Bay M, and Beach Blvd + Hodges Blvd in around 3h 58m.

Train operators

Bus operators

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