There are 6 ways to get from Orlando to Mesa by plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Orlando
best- Fly from Orlando (MCO) to Phoenix (PHX)plane MCO - PHX
6h 47m$134–804Bus via Ciudad Juárez
- Take the bus from Orlando - RedCoach Station, FL to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus
- Take the bus from Tallahassee to Houston Bus Stationbus
- Take the bus from Houston Bus Station to El Paso Bus Stationbus
- Take the bus from El Paso to Phoenixbus
47h 17m$351–560Train, bus
- Take the train from Orlando to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Flagstafftrain
- Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus
3d 3h$912–2,017Drive 2,072.4 mi
- Drive from Orlando to Mesacar 2,072.4 mi
34h$379–547Bus to Tampa, fly
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Phoenix (PHX)plane TPA - PHX
8h 58m$157–426Bus
- Take the bus from Orlando Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Phoenix Bus Stationbus
2d 3h$349–592
Orlando to Mesa by train, bus, and tram
Comparing Your Travel Options
The cheapest way to get from Orlando to Mesa is to bus and fly which costs $150 - $430 and takes 8h 58m.
The fastest way to get from Orlando to Mesa is to fly which takes 6h 47m and costs $130 - $850.
No, there is no direct bus from Orlando station to Mesa. However, there are services departing from Orlando - RedCoach Station, FL and arriving at Phoenix via Old St Augustine at Intramural Field, Tallahassee, Houston Bus Station and El Paso. The journey, including transfers, takes approximately 47h 17m.
The distance between Orlando and Mesa is 1885 miles. The road distance is 2084.5 miles.
The best way to get from Orlando to Mesa without a car is to bus via Ciudad Juárez which takes 47h 17m and costs $350 - $600.
It takes approximately 6h 47m to get from Orlando to Mesa, including transfers.
Orlando to Mesa bus services, operated by RedCoach, depart from Orlando - RedCoach Station, FL.
The best way to get from Orlando to Mesa is to fly which takes 6h 47m and costs $130 - $850. Alternatively, you can bus via Ciudad Juárez, which costs $350 - $600 and takes 47h 17m.
Orlando to Mesa bus services, operated by RedCoach, arrive at Tallahassee - FSU - Old St Augustine at Intramural Field station.
Mesa is 3h behind Orlando. It is currently 7:00 AM in Orlando and 4:00 AM in Mesa.
What companies run services between Orlando, FL, USA and Mesa, AZ, USA?
American Airlines and Southwest Airlines fly from Orlando (MCO) to Phoenix (PHX) every 3 hours. Alternatively, you can take a bus from Orlando - RedCoach Station, FL to Mesa Dr/Main St via Old St Augustine at Intramural Field, Tallahassee, Houston Bus Station, El Paso Bus Station, El Paso, Phoenix, and 24th St/Jefferson in around 47h 17m.
- Website
- southwest.com
Flights from Orlando to Phoenix
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $130–550
Flights from Orlando to Phoenix via Houston Hobby Apt
- Ave. Duration
- 6h 12m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $130–550
Flights from Orlando to Phoenix via Dallas
- Ave. Duration
- 6h 12m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $130–550
Flights from Orlando to Phoenix via Austin
- Ave. Duration
- 6h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–550
Flights from Orlando to Phoenix via San Antonio
- Ave. Duration
- 6h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–550
Flights from Tampa to Phoenix
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $130–600
Flights from Tampa to Phoenix via Houston Hobby Apt
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $130–600
Flights from Tampa to Phoenix via San Antonio
- Ave. Duration
- 6h 12m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $130–600
Flights from Tampa to Phoenix via Austin
- Ave. Duration
- 6h 5m
- When
- Sunday
- Estimated price
- $130–600
Flights from Tampa to Phoenix via New Orleans
- Ave. Duration
- 6h 10m
- When
- Tuesday and Wednesday
- Estimated price
- $130–600
Flights from Tampa to Phoenix via Dallas
- Ave. Duration
- 6h 16m
- When
- Tuesday to Friday
- Estimated price
- $130–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Chicago Union Station
- Ave. Duration
- 38h 55m
- Frequency
- Once daily
- Estimated price
- $440–1,000
- Website
- Amtrak
Train from Chicago Union Station to Flagstaff
- Ave. Duration
- 31h 44m
- Frequency
- Once daily
- Estimated price
- $440–1,000
- Website
- Amtrak
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Orlando - RedCoach Station, FL to Tallahassee - FSU - Old St Augustine at Intramural Field
- Ave. Duration
- 4h 55m
- Frequency
- 3 times a day
- Estimated price
- $65–95
- Website
- RedCoach
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Orlando to Mesa is 2085 miles. It takes approximately 34h to drive from Orlando to Mesa.
Book your Orlando to Mesa bus tickets online with Omio.
There are 2761+ hotels available in Mesa.







