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How to get fromOrlando to Missouriby plane, bus (Flixbus, Greyhound), car, or bus

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There are 9 ways to get from Orlando to Missouri by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Lambert–St. Louis International Airport

    best
    1. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    4h 23m
    $185–495

  2. Fly Orlando Sanford to Springfield-Branson National Airport

    cheapest
    1. Fly from Orlando Sanford (SFB) to Springfield-Branson National Airport (SGF)plane plane SFB - SGF
    3h 26m
    $162–523

  3. Bus

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    24h 55m
    $187–370

  4. Drive 1,190 mi

    1. Drive from Orlando to Kansas Citycar car 1,190 mi
    21h 19m
    $218–314

  5. Fly Orlando Sanford to Midamerica St. Louis Airport

    1. Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane plane SFB - BLV
    4h 9m
    $167–515

  6. Fly Orlando to Kansas City

    1. Fly from Orlando (MCO) to Kansas City (MCI)plane plane MCO - MCI
    5h 45m
    $212–1,102

  7. Bus to Tampa, fly to Lambert–St. Louis International Airport

    1. Take the bus from Orlando Bus Station to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    6h 38m
    $438–2,030

  8. Fly Orlando Sanford to Columbia Regional Airport

    1. Fly from Orlando Sanford (SFB) to Columbia Regional Airport (COU)plane plane SFB - COU
    3h 30m
    $201–568

  9. Bus via New South Memphis

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Kansas Citybus bus
    26h 55m
    $232–395

Orlando to Missouri by bus

Calendar12Weekly Buses
Duration24h 55mAverage Duration
Ticket$187Cheapest Price
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Questions & Answers

Map of how to get from Orlando to Missouri.ExpandLaunch map view
  • Distance: 912 mi
  • Duration: 4h 23m

What companies run services between Orlando, FL, USA and Missouri, USA?

Frontier Airlines, Southwest Airlines, and Delta fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Orlando Bus Station to Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station in around 24h 55m.

Airlines
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