There are 8 ways to get from Orlando to Missouri by plane, bus (Flixbus, Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Lambert–St. Louis International Airport
best- Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane MCO - STL
4h 28m$185–325Fly Orlando Sanford to Springfield-Branson National Airport
cheapest- Fly from Orlando Sanford (SFB) to Springfield-Branson National Airport (SGF)plane SFB - SGF
3h 24m$162–533Bus
- Take the bus from Orlando Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Kansas City Bus Stationbus
24h 55m$179–312Drive 1,190 mi
- Drive from Orlando to Kansas Citycar 1,190 mi
21h 19m$218–314Fly Orlando to Kansas City
- Fly from Orlando (MCO) to Kansas City (MCI)plane MCO - MCI
5h 50m$212–1,102Fly Orlando Sanford to Midamerica St. Louis Airport
- Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane SFB - BLV
4h 1m$167–535Bus to Tampa, fly to Lambert–St. Louis International Airport
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane TPA - STL
6h 43m$567–2,026Fly Orlando Sanford to Columbia Regional Airport
- Fly from Orlando Sanford (SFB) to Columbia Regional Airport (COU)plane SFB - COU
3h 30m$196–588
Orlando to Missouri by bus
Comparing Your Travel Options
The cheapest way to get from Orlando to Missouri is to fly which costs $180 - $330 and takes 4h 28m.
The fastest way to get from Orlando to Missouri is to fly which takes 3h 24m and costs $160 - $550.
No, there is no direct bus from Orlando station to Missouri station. However, there are services departing from Orlando Bus Station and arriving at Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 24h 55m.
The distance between Orlando and Missouri is 917 miles. The road distance is 1197 miles.
The best way to get from Orlando to Missouri without a car is to bus which takes 24h 55m and costs $170 - $320.
It takes approximately 4h 28m to get from Orlando to Missouri, including transfers.
Orlando to Missouri bus services, operated by Flixbus USA, depart from Orlando Bus Station.
The best way to get from Orlando to Missouri is to fly which takes 4h 28m and costs $180 - $330. Alternatively, you can bus, which costs $170 - $320 and takes 24h 55m.
Orlando to Missouri bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Missouri is 1h behind Orlando. It is currently 2:54 PM in Orlando and 1:54 PM in Missouri.
What companies run services between Orlando, FL, USA and Missouri, USA?
Frontier Airlines, Southwest Airlines, and Delta fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Orlando Bus Station to Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station in around 24h 55m.
- Website
- southwest.com
Flights from Orlando to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $100–600
Flights from Orlando to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 12m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Orlando to Kansas City
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $130–700
Flights from Orlando to Kansas City via Nashville
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $130–700
Flights from Orlando to Kansas City via Lambert–St. Louis International Airport
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $140–700
Flights from Tampa to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 29m
- When
- Every day
- Estimated price
- $110–600
Flights from Tampa to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 22m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $110–600
Flights from Tampa to Lambert–St. Louis International Airport via New Orleans
- Ave. Duration
- 4h 30m
- When
- Tuesday and Wednesday
- Estimated price
- $130–650
Flights from Tampa to Lambert–St. Louis International Airport via Columbus
- Ave. Duration
- 4h 30m
- When
- Tuesday and Wednesday
- Estimated price
- $140–700
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 15m
- Frequency
- Every 4 hours
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 21m
- Frequency
- 5 times a week
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $12–19
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Orlando to Missouri is 1197 miles. It takes approximately 21h 19m to drive from Orlando to Missouri.
Book your Orlando to Missouri bus tickets online with Omio and FlixBus.
There are 497+ hotels available in Missouri.

