Rome2Rio

How to get fromOrlando to Mount Pleasantby train (Amtrak), car, plane, or bus

Find Transport to Mount Pleasant

See all options

There are 4 ways to get from Orlando to Mount Pleasant by train (Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Orlando to Charleston Amtrak Stationtrain train Silver Meteor
    8h 6m
    $168–311

  2. Drive 383.1 mi

    cheapest
    1. Drive from Orlando to Mount Pleasantcar car 383.1 mi
    6h 37m
    $70–101

  3. Fly from Orlando, line 41 bus

    1. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    2. Take the bus from Mary St / Meeting St to Coleman Blvd / Chuck Dawley Blvdbus bus
    5h 41m
    $71–256

  4. Bus to Tampa, fly

    1. Take the bus from Orlando Bus Station to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    8h 5m
    $159–371

Orlando (MCO) to Charleston International Airport (CHS) flights

Calendar7Weekly Planes
Duration1h 28mAverage Duration
Ticket$65Cheapest Price
See schedules

Questions & Answers

Map of how to get from Orlando to Mount Pleasant.ExpandLaunch map view
  • Distance: 407.8 mi
  • Duration: 8h 6m

What companies run services between Orlando, FL, USA and Mount Pleasant, SC, USA?

Amtrak operates a train from Orlando to Charleston Amtrak Station once daily. Tickets cost $120–270 and the journey takes 7h 49m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers