There are 5 ways to get from Orlando to Orangeburg by plane, car, bus (Flixbus), train (Amtrak), or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Charleston International Airport, drive
best- Fly from Orlando (MCO) to Charleston International Airport (CHS)plane MCO - CHS
- Drive from Charleston-Airport-CHS to Orangeburgcar
3h 55m$104–280Drive 378.3 mi
cheapest- Drive from Orlando to Orangeburgcar 378.3 mi
6h 43m$67–97Bus (Flixbus)
- Take the bus from Orlando Bus Station to Orangeburgbus FlixBus 2433
7h 23m$71–102Train (Amtrak)
- Take the train from Orlando to Denmark Amtrak Stationtrain Floridian
8h 44m$276–404Fly to Columbia, taxi
- Fly from Orlando (MCO) to Columbia (CAE)plane MCO - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
5h 26m$182–502
Orlando (MCO) to Charleston International Airport (CHS) flights
Comparing Your Travel Options
The cheapest way to get from Orlando to Orangeburg is to drive which costs $65 - $100 and takes 6h 43m.
The fastest way to get from Orlando to Orangeburg is to fly and drive which takes 3h 55m and costs $100 - $280.
No, there is no direct bus from Orlando station to Orangeburg. However, there are services departing from Orlando Bus Station and arriving at Orangeburg via . The journey, including transfers, takes approximately 7h 23m.
No, there is no direct train from Orlando to Orangeburg station. However, there are services departing from Orlando and arriving at Denmark Amtrak Station via . The journey, including transfers, takes approximately 8h 44m.
The distance between Orlando and Orangeburg is 405 miles. The road distance is 380.5 miles.
The best way to get from Orlando to Orangeburg without a car is to bus which takes 7h 23m and costs $70 - $110.
It takes approximately 3h 55m to get from Orlando to Orangeburg, including transfers.
Orlando to Orangeburg bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Orangeburg train services, operated by Amtrak, depart from Orlando station.
The best way to get from Orlando to Orangeburg is to bus which takes 7h 23m and costs $70 - $110. Alternatively, you can train, which costs $270 - $410 and takes 8h 44m.
What companies run services between Orlando, FL, USA and Orangeburg, SC, USA?
Flixbus USA operates a bus from Orlando Bus Station to Orangeburg once daily. Tickets cost $60–95 and the journey takes 7h 20m. Alternatively, Amtrak operates a train from Orlando to Denmark Amtrak Station once daily. Tickets cost $210–330 and the journey takes 8h 12m.
- Website
- delta.com
Flights from Orlando to Charleston International Airport via Atlanta
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $75–430
Flights from Orlando to Columbia via Atlanta
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $60–350
Flights from Orlando to Columbia via New York La Guardia
- Ave. Duration
- 6h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- aa.com
Flights from Orlando to Columbia via Charlotte
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $60–350
Flights from Orlando to Columbia via Reagan Washington
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $95–450
Flights from Orlando to Columbia via New York La Guardia
- Ave. Duration
- 6h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Orlando to Columbia via Miami
- Ave. Duration
- 6h 55m
- When
- Saturday
- Estimated price
- $70–380
Flights from Orlando to Columbia via Philadelphia
- Ave. Duration
- 7h 2m
- When
- Every day
- Estimated price
- $100–490
- Website
- flybreeze.com
Flights from Orlando to Charleston International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $90–230
- Website
- united.com
Flights from Orlando to Columbia via Washington Dulles
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $90–450
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Denmark Amtrak Station
- Ave. Duration
- 8h 12m
- Frequency
- Once daily
- Estimated price
- $210–330
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Orangeburg
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $60–95
- Schedules at
- Flixbus USA
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Orlando to Orangeburg bus services, operated by Flixbus USA, arrive at Orangeburg station.
Orlando to Orangeburg train services, operated by Amtrak, arrive at Denmark Amtrak Station.
Yes, the driving distance between Orlando to Orangeburg is 381 miles. It takes approximately 6h 43m to drive from Orlando to Orangeburg.
Book your Orlando to Orangeburg bus tickets online with Omio.
There are 21+ hotels available in Orangeburg.