There are 6 ways to get from Orlando to Orangeburg by bus (Flixbus), train (Amtrak), car, plane, taxi, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Orlando Bus Station to Orangeburgbus FlixBus 2433
7h 23m$71–112Drive 378.3 mi
cheapest- Drive from Orlando to Orangeburgcar 378.3 mi
6h 43m$69–100Train (Amtrak)
- Take the train from Orlando to Denmark Amtrak Stationtrain Floridian
8h 44m$190–330Fly to Columbia, taxi
- Fly from Orlando (MCO) to Columbia (CAE)plane MCO - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
5h 44m$262–952Train, bus
- Take the train from Orlando to Charleston Amtrak Stationtrain Silver Meteor
- Take the bus from Charleston Bus Station to Orangeburgbus Greyhound US0643S / ...
10h 7m$148–290Fly to Myrtle Beach, bus
- Fly from Orlando (MCO) to Myrtle Beach (MYR)plane MCO - MYR
- Take the bus from Myrtle Beach Bus Station to Orangeburgbus
7h 44m$137–396
Orlando (MCO) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Orlando to Orangeburg is to bus which costs $70 - $120 and takes 7h 23m.
The fastest way to get from Orlando to Orangeburg is to fly and taxi which takes 5h 44m and costs $260 - $950.
No, there is no direct bus from Orlando station to Orangeburg. However, there are services departing from Orlando Bus Station and arriving at Orangeburg via . The journey, including transfers, takes approximately 7h 23m.
No, there is no direct train from Orlando to Orangeburg station. However, there are services departing from Orlando and arriving at Denmark Amtrak Station via . The journey, including transfers, takes approximately 8h 44m.
The distance between Orlando and Orangeburg is 391 miles. The road distance is 380.5 miles.
The best way to get from Orlando to Orangeburg without a car is to bus which takes 7h 23m and costs $70 - $120.
It takes approximately 7h 23m to get from Orlando to Orangeburg, including transfers.
Orlando to Orangeburg bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Orangeburg train services, operated by Amtrak, depart from Orlando station.
The best way to get from Orlando to Orangeburg is to bus which takes 7h 23m and costs $70 - $120. Alternatively, you can train, which costs $190 - $330 and takes 8h 44m.
What companies run services between Orlando, FL, USA and Orangeburg, SC, USA?
Flixbus USA operates a bus from Orlando Bus Station to Orangeburg once daily. Tickets cost $60–110 and the journey takes 7h 20m. Alternatively, Amtrak operates a train from Orlando to Denmark Amtrak Station once daily. Tickets cost $120–250 and the journey takes 8h 12m.
- Website
- aa.com
Flights from Orlando to Columbia via Charlotte
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $140–800
Flights from Orlando to Columbia via Reagan Washington
- Ave. Duration
- 5h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $240–1,100
Flights from Orlando to Columbia via Miami
- Ave. Duration
- 6h 17m
- When
- Saturday
- Estimated price
- $170–900
Flights from Orlando to Columbia via Philadelphia
- Ave. Duration
- 7h 9m
- When
- Every day
- Estimated price
- $270–1,200
Flights from Orlando to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $55–290
- Website
- delta.com
Flights from Orlando to Columbia via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $150–800
Flights from Orlando to Columbia via New York La Guardia
- Ave. Duration
- 7h 56m
- When
- Every day
- Estimated price
- $300–1,300
Flights from Orlando to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–310
- Website
- united.com
Flights from Orlando to Columbia via Washington Dulles
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- flybreeze.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–280
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Denmark Amtrak Station
- Ave. Duration
- 8h 12m
- Frequency
- Once daily
- Estimated price
- $120–250
- Website
- https://www.amtrak.com/home.html
Train from Orlando to Charleston Amtrak Station
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- $120–260
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando Bus Station to Orangeburg
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Charleston Bus Station to Orangeburg
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $11–21
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Orangeburg
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
Want to know more about travelling around United States
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More Questions & Answers
Orlando to Orangeburg bus services, operated by Flixbus USA, arrive at Orangeburg station.
Orlando to Orangeburg train services, operated by Amtrak, arrive at Denmark Amtrak Station.
Yes, the driving distance between Orlando to Orangeburg is 381 miles. It takes approximately 6h 43m to drive from Orlando to Orangeburg.
Book your Orlando to Orangeburg bus tickets online with Omio.
There are 22+ hotels available in Orangeburg.






