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How to get fromOrlando to Picayuneby plane, taxi, bus (Greyhound), train (Amtrak), car, train, or bus

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There are 8 ways to get from Orlando to Picayune by plane, taxi, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Gulfport-Biloxi Regional Airport, taxi

    best
    1. Fly from Orlando (MCO) to Gulfport-Biloxi Regional Airport (GPT)plane plane MCO - GPT
    2. Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi taxi
    4h 9m
    $222–792

  2. Drive 607.1 mi

    cheapest
    1. Drive from Orlando to Picayunecar car 607.1 mi
    10h 3m
    $111–160

  3. Bus

    1. Take the bus from Orlando - RedCoach Station, FL to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to Slidellbus bus
    16h 27m
    $181–303

  4. Train (Amtrak)

    1. Take the train from Orlando to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the train from Greensboro to Picayune Amtrak Stationtrain train
    36h 18m
    $491–1,009

  5. Fly Orlando to Louis Armstrong New Orleans International Airport, train

    1. Fly from Orlando (MCO) to Louis Armstrong New Orleans International Airport (MSY)plane plane MCO - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train
    6h 45m
    $112–532

  6. Bus to Tampa, fly to Gulfport-Biloxi Regional Airport, taxi

    1. Take the bus from Orlando Bus Station to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Gulfport-Biloxi Regional Airport (GPT)plane plane TPA - GPT
    3. Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi taxi
    6h 19m
    $285–1,117

  7. Bus, train

    1. Take the bus from Orlando - RedCoach Station, FL to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    4. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train
    18h 44m
    $146–278

  8. Bus, train via Florida Mall

    1. Take the bus from Orlando to Tallahasseebus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    4. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train
    19h 50m
    $120–227

Orlando to Picayune by train (Amtrak)

Calendar7Weekly Trains
Duration36h 18mAverage Duration
Ticket$491Cheapest Price
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Questions & Answers

Map of how to get from Orlando to Picayune.ExpandLaunch map view
  • Distance: 548.6 mi
  • Duration: 4h 9m

What companies run services between Orlando, FL, USA and Picayune, MS, USA?

You can take a bus from Orlando - RedCoach Station, FL to Picayune via Old St Augustine at Intramural Field, Tallahassee, Mobile Bus Station, and Slidell in around 16h 27m. Alternatively, you can take a train from Orlando to Picayune Amtrak Station via Cary and Greensboro in around 36h 18m.

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