There are 5 ways to get from Orlando to Sanibel by plane, bus (Flixbus), car, bus, taxi, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Orlando (MCO) to Ft. Myers (RSW)plane MCO - RSW
2h 52m$422–637Drive 171.4 mi
cheapest- Drive from Orlando to Sanibelcar 171.4 mi
3h 38m$32–46Bus (Flixbus)
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus FlixBus 2421
5h 43m$87–118Bus, taxi
- Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus Amtrak Thruway Connecting Service
- Take the taxi from Fort Myers Amtrak Bus Stop to Sanibeltaxi
6h 22m$127–173Train, bus
- Take the train from Orlando to Tampatrain Floridian
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus FlixBus 2421
7h 3m$102–156
Orlando (MCO) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from Orlando to Sanibel is to drive which costs $30 - $45 and takes 3h 38m.
The fastest way to get from Orlando to Sanibel is to fly which takes 2h 52m and costs $420 - $650.
No, there is no direct bus from Orlando station to Sanibel. However, there are services departing from Orlando Bus Station and arriving at Fort Myers Bus Stop via . The journey, including transfers, takes approximately 5h 43m.
The distance between Orlando and Sanibel is 177 miles. The road distance is 172.4 miles.
The best way to get from Orlando to Sanibel without a car is to bus which takes 5h 43m and costs $85 - $120.
It takes approximately 2h 52m to get from Orlando to Sanibel, including transfers.
Orlando to Sanibel bus services, operated by Flixbus USA, depart from Orlando Bus Station.
The best way to get from Orlando to Sanibel is to fly which takes 2h 52m and costs $420 - $650. Alternatively, you can bus, which costs $85 - $120 and takes 5h 43m.
Orlando to Sanibel bus services, operated by Flixbus USA, arrive at Fort Myers Bus Stop station.
Yes, the driving distance between Orlando to Sanibel is 172 miles. It takes approximately 3h 38m to drive from Orlando to Sanibel.
What companies run services between Orlando, FL, USA and Sanibel, FL, USA?
Southwest Airlines flies from Orlando (MCO) to Ft. Myers (RSW) twice daily. Alternatively, Flixbus USA operates a bus from Orlando Bus Station to Fort Myers Bus Stop 3 times a day. Tickets cost $30–50 and the journey takes 5h 10m.
- Website
- southwest.com
Flights from Orlando to Ft. Myers
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $40–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Tampa
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $23–55
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $19–30
- Schedules at
- Flixbus USA
- Ave. Duration
- 37 min
- Estimated price
- $70–90
EJ Taxi
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 3724+ hotels available in Sanibel.






