There are 5 ways to get from Orlando to Sanibel Island by plane, bus (Flixbus), car, bus (Amtrak), train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Orlando (MCO) to Ft. Myers (RSW)plane MCO - RSW
2h 50m$367–692Drive 170.3 mi
cheapest- Drive from Orlando to Sanibel Islandcar 170.3 mi
3h 36m$32–45Bus (Flixbus)
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus FlixBus 2421
5h 40m$90–128Bus via Tice (Amtrak)
- Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus Amtrak Thruway Connecting Service
6h 20m$145–195Train, bus
- Take the train from Orlando to Tampatrain Floridian
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus FlixBus 2421
7h$109–174
Orlando (MCO) to Ft. Myers (RSW) flights
Questions & Answers
The cheapest way to get from Orlando to Sanibel Island is to drive which costs $30 - $45 and takes 3h 36m.
The fastest way to get from Orlando to Sanibel Island is to fly which takes 2h 50m and costs $360 - $700.
No, there is no direct bus from Orlando station to Sanibel Island. However, there are services departing from Orlando Bus Station and arriving at Fort Myers Bus Stop via . The journey, including transfers, takes approximately 5h 40m.
The distance between Orlando and Sanibel Island is 175 miles. The road distance is 171.3 miles.
The best way to get from Orlando to Sanibel Island without a car is to bus which takes 5h 40m and costs $90 - $130.
It takes approximately 2h 50m to get from Orlando to Sanibel Island, including transfers.
Orlando to Sanibel Island bus services, operated by Flixbus USA, depart from Orlando Bus Station.
The best way to get from Orlando to Sanibel Island is to fly which takes 2h 50m and costs $360 - $700. Alternatively, you can bus, which costs $90 - $130 and takes 5h 40m.
Orlando to Sanibel Island bus services, operated by Flixbus USA, arrive at Fort Myers Bus Stop station.
Yes, the driving distance between Orlando to Sanibel Island is 171 miles. It takes approximately 3h 36m to drive from Orlando to Sanibel Island.
What companies run services between Orlando, FL, USA and Sanibel Island, FL, USA?
Southwest Airlines flies from Orlando (MCO) to Ft. Myers (RSW) twice daily. Alternatively, Flixbus USA operates a bus from Orlando Bus Station to Fort Myers Bus Stop 3 times a day. Tickets cost $35–60 and the journey takes 5h 10m.
- Website
- southwest.com
Flights from Orlando to Ft. Myers
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $35–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Tampa
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $29–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- flixbus.com
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Orlando to Fort Myers Amtrak Bus Stop
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- https://www.amtrak.com/home.html
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More Questions & Answers
There are 4314+ hotels available in Sanibel Island.






