There are 8 ways to get from Orlando to Seneca by plane, taxi, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Greenville–Spartanburg International Airport, taxi
best- Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane MCO - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
4h 3m$272–822Fly Orlando to Asheville Regional Airport, drive
cheapest- Fly from Orlando (MCO) to Asheville Regional Airport (AVL)plane MCO - AVL
- Drive from Asheville-Airport-AVL to Senecacar
4h 51m$69–331Bus, taxi
- Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
11h 32m$254–476Drive 483.5 mi
- Drive from Orlando to Senecacar 483.5 mi
10h 1m$89–128Fly Orlando Sanford to Asheville Regional Airport, drive
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from Asheville-Airport-AVL to Senecacar
4h 1m$128–422Fly Orlando Sanford to Greenville–Spartanburg International Airport, taxi
- Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane SFB - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
3h 10m$276–733Bus, train
- Take the bus from Orlando Bus Station to Charlotte Bus Stationbus FlixBus 2433
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain Crescent
14h 57m$156–264Bus, taxi via Gainesville
- Take the bus from Orlando Bus Station to Gainesville Bus Stopbus
- Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
15h 22m$211–407
Orlando (MCO) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Orlando to Seneca is to drive which costs $85 - $130 and takes 10h 1m.
The fastest way to get from Orlando to Seneca is to fly and taxi which takes 3h 10m and costs $270 - $750.
The distance between Orlando and Seneca is 518 miles. The road distance is 486.4 miles.
The best way to get from Orlando to Seneca without a car is to bus and taxi which takes 11h 32m and costs $250 - $480.
It takes approximately 4h 3m to get from Orlando to Seneca, including transfers.
Yes, the driving distance between Orlando to Seneca is 486 miles. It takes approximately 10h 1m to drive from Orlando to Seneca.
There are 150+ hotels available in Seneca.
What companies run services between Orlando, FL, USA and Seneca, SC, USA?
There is no direct connection from Orlando to Seneca. However, you can take the line 42 bus to Orlando International Airport, walk to Orlando (MCO) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take the bus to Atlanta - Civic Center MARTA Station, walk to Civic Center Station, take the subway to Doraville Station, walk to Atlanta, take the bus to Flying J - Commerce, then take the taxi to Seneca.
- Website
- aa.com
Flights from Orlando to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $85–480
Flights from Orlando to Greenville–Spartanburg International Airport via Miami
- Ave. Duration
- 4h 17m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
Flights from Orlando to Asheville Regional Airport via Charlotte
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $60–320
- Website
- delta.com
Flights from Orlando to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $90–480
Flights from Orlando to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $60–330
- Website
- allegiantair.com
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $55–330
Flights from Orlando to Asheville Regional Airport
- Ave. Duration
- 1h 45m
- When
- Monday and Friday
- Estimated price
- $55–310
Flights from Orlando Sanford to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 28m
- When
- Sunday and Thursday
- Estimated price
- $85–490
- Website
- southwest.com
Flights from Orlando to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 11m
- When
- Sunday and Saturday
- Estimated price
- $120–600
- Website
- flybreeze.com
Flights from Orlando to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 41m
- When
- Monday and Friday
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Station
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $110–210
- Website
- https://www.redcoachusa.com
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando Bus Station to Charlotte Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $85–140
- Schedules at
- flixbus.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Gainesville Bus Stop
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Gainesville Bus Stop to Atlanta Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Orlando Bus Station to Gainesville Bus Stop
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Bus from Gainesville Bus Stop to Atlanta Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
- Ave. Duration
- 56 min
- Estimated price
- $100–170
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
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