There are 6 ways to get from Orlando to Tupelo by plane, car, bus (Flixbus, Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Golden Triangle Regional Airport, drive
best- Fly from Orlando (MCO) to Golden Triangle Regional Airport (GTR)plane MCO - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
6h 22m$78–389Bus
- Take the bus from Orlando Bus Station to Atlanta Bus Stationbus FlixBus N2401 / ...
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
14h 14m$115–191Drive 645.9 mi
- Drive from Orlando to Tupelocar 645.9 mi
11h 34m$118–171Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Orlando (MCO) to Birmingham–Shuttlesworth International Airport (BHM)plane MCO - BHM
- Drive from Birmingham-Airport-BHM to Tupelocar
5h 16m$266–512Fly to Huntsville International Airport-Carl T Jones Field, drive
- Fly from Orlando (MCO) to Huntsville International Airport-Carl T Jones Field (HSV)plane MCO - HSV
- Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar
5h 42m$135–337Fly to Memphis, bus
- Fly from Orlando (MCO) to Memphis (MEM)plane MCO - MEM
- Take the bus from Memphis Bus Station to Tupelobus
7h 27m$159–792
Orlando (MCO) to Golden Triangle Regional Airport (GTR) flights
Comparing Your Travel Options
The cheapest way to get from Orlando to Tupelo is to bus which costs $110 - $200 and takes 14h 14m.
The fastest way to get from Orlando to Tupelo is to fly and drive which takes 5h 16m and costs $260 - $550.
No, there is no direct bus from Orlando station to Tupelo. However, there are services departing from Orlando Bus Station and arriving at Tupelo via Atlanta Bus Station. The journey, including transfers, takes approximately 14h 14m.
The distance between Orlando and Tupelo is 635 miles. The road distance is 649.6 miles.
The best way to get from Orlando to Tupelo without a car is to bus which takes 14h 14m and costs $110 - $200.
It takes approximately 6h 22m to get from Orlando to Tupelo, including transfers.
Orlando to Tupelo bus services, operated by Flixbus USA, depart from Orlando Bus Station.
Orlando to Tupelo bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Tupelo is 1h behind Orlando. It is currently 10:56 PM in Orlando and 9:56 PM in Tupelo.
Yes, the driving distance between Orlando to Tupelo is 650 miles. It takes approximately 11h 34m to drive from Orlando to Tupelo.
What companies run services between Orlando, FL, USA and Tupelo, MS, USA?
You can take a bus from Orlando Bus Station to Tupelo via Atlanta Bus Station and Tupelo in around 14h 14m.
- Website
- delta.com
Flights from Orlando to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $65–370
Flights from Orlando to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $120–700
Flights from Orlando to Huntsville International Airport-Carl T Jones Field via Atlanta
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $90–550
Flights from Orlando to Memphis via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $130–750
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 15m
- Frequency
- Every 4 hours
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
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Booking & Getting There
Book your Orlando to Tupelo bus tickets online with Omio.
There are 35+ hotels available in Tupelo.