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How to get fromOrlando to Winston-Salemby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Winston-Salem

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There are 6 ways to get from Orlando to Winston-Salem by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Orlando (MCO) to Piedmont Triad International Airport (GSO)plane plane MCO - GSO
    4h 10m
    $81–375

  2. Bus

    1. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus FlixBus 2433
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    12h 25m
    $95–141

  3. Train, bus via Fayetteville

    1. Take the train from Orlando to Fayetteville Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0647S
    16h 21m
    $344–528

  4. Drive  597.2 mi

    1. Drive from Orlando to Winston-Salemcar car 597.2 mi
    10h
    $109–158

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane plane MCO - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 7m
    $119–398

  6. Train, bus

    1. Take the train from Orlando to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    17h 30m
    $392–607

Orlando to Winston-Salem by bus

Calendar7Weekly Buses
Duration12h 25mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Orlando to Winston-Salem.ExpandLaunch map view
  • Distance: 575.8 mi
  • Duration: 4h 10m

What companies run services between Orlando, FL, USA and Winston-Salem, NC, USA?

Breeze Airways, Delta, and two other airlines fly from Orlando (MCO) to Piedmont Triad International Airport (GSO) every 2 hours. Alternatively, you can take a bus from Orlando Bus Station to Winston Salem(Trans Center) via Charlotte Bus Station in around 12h 25m.

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