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How to get fromOsage Beach to Knoxvilleby car, plane, taxi, train, bus, or shuttle

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There are 10 ways to get from Osage Beach to Knoxville by car, plane, taxi, train, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Columbia Regional Airport, fly to Mcghee Tyson Airport

    best
    1. Drive from Osage Beach to Columbia Regional Airport (COU)car car
    2. Fly from Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS)plane plane COU - TYS
    6h 6m
    $207–838

  2. Drive 596.5 mi

    cheapest
    1. Drive from Osage Beach to Knoxvillecar car 596.5 mi
    11h 35m
    $109–158

  3. Taxi, train, bus

    1. Take the taxi from Osage Beach to Jefferson City Stationtaxi taxi
    2. Take the train from Jefferson City Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    43h 46m
    $738–1,308

  4. Taxi, shuttle, bus

    1. Take the taxi from Osage Beach to Ft Wood - St Robert - Waynesvilletaxi taxi
    2. Take a shuttle bus from Ft Wood - St Robert - Waynesville to St Louis International Airportshuttle bus
    3. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    44h 3m
    $593–848

  5. Drive to Springfield-Branson National Airport, fly to Mcghee Tyson Airport

    1. Drive from Osage Beach to Springfield-Branson National Airport (SGF)car car
    2. Fly from Springfield-Branson National Airport (SGF) to Mcghee Tyson Airport (TYS)plane plane SGF - TYS
    6h 2m
    $201–794

  6. Taxi to Waynesville-St. Robert Regional Airport, fly to Nashville, drive

    1. Take the taxi from Osage Beach to Waynesville-St. Robert Regional Airport (TBN)taxi taxi
    2. Fly from Waynesville-St. Robert Regional Airport (TBN) to Nashville (BNA)plane plane TBN - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    5h 34m
    $249–758

  7. Taxi, shuttle to Lambert–St. Louis International Airport, fly to Mcghee Tyson Airport

    1. Take the taxi from Osage Beach to Ft Wood - St Robert - Waynesvilletaxi taxi
    2. Take a shuttle bus from Ft Wood - St Robert - Waynesville to St Louis International Airportshuttle bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    9h 9m
    $422–1,102

  8. Taxi to Waynesville-St. Robert Regional Airport, fly to Mcghee Tyson Airport

    1. Take the taxi from Osage Beach to Waynesville-St. Robert Regional Airport (TBN)taxi taxi
    2. Fly from Waynesville-St. Robert Regional Airport (TBN) to Mcghee Tyson Airport (TYS)plane plane TBN - TYS
    6h 7m
    $379–1,128

  9. Taxi, train, bus via Ossining

    1. Take the taxi from Osage Beach to Jefferson City Stationtaxi taxi
    2. Take the train from Jefferson City Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    44h 24m
    $693–1,235

  10. Taxi, bus

    1. Take the taxi from Osage Beach to Jefferson Citytaxi taxi
    2. Take the bus from Jefferson City to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to New York City Chinatownbus bus
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d
    $400–609

Columbia Regional Airport (COU) to Mcghee Tyson Airport (TYS) flights

Calendar62Weekly Planes
Duration5h 18mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from Osage Beach to Knoxville.ExpandLaunch map view
  • Distance: 578.7 mi
  • Duration: 6h 6m

What companies run services between Osage Beach, MO, USA and Knoxville, TN, USA?

There is no direct connection from Osage Beach to Knoxville. However, you can drive to Columbia Regional Airport (COU) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take the taxi to Jefferson City Station, take the train to Chicago Union Station, take the train to Ny Moynihan Train Hall At Penn Station, walk to 34 St-Herald Sq, take the subway to East Broadway, walk to New York, take the bus to Knoxville, then take the taxi to Knoxville.

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