There are 4 ways to get from Otay Mesa to Anaheim by tram, bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Tram, bus
best- Take the tram from Iris Avenue Station to Old Town Stationtram Blue
- Take the bus from San Diego to Anaheim Regional Transportation Intermodal Centerbus FlixBus N2003 / ...
3h 47mDrive 111.1 mi
cheapest- Drive from Otay Mesa to Anaheimcar 111.1 mi
2h$19–28Tram, train
- Take the tram from Iris Avenue Station to America Plaza Stationtram Blue
- Take the train from San Diego to Fullerton Amtrak Stationtrain Pacific Surfliner
4h 13m$60–109Bus, line 83 bus
- Take the bus from San Ysidro to Santa Anabus Lxus 3126 / ...
- Take the bus from Santa Ana-Santiago to Ball-Oxbus 83
4h 6m$24–40
Comparing Your Travel Options
The cheapest way to get from Otay Mesa to Anaheim is to drive which costs $19 - $28 and takes 2h.
The fastest way to get from Otay Mesa to Anaheim is to drive which takes 2h and costs $19 - $28.
No, there is no direct bus from Otay Mesa to Anaheim. However, there are services departing from Otay Mesa Rd & Cactus Rd and arriving at Ball-Ox via Iris Avenue Transit Center, San Ysidro and Santa Ana-Santiago. The journey, including transfers, takes approximately 4h 6m.
No, there is no direct train from Otay Mesa station to Anaheim station. However, there are services departing from Iris Avenue Station and arriving at Fullerton Amtrak Station via San Diego. The journey, including transfers, takes approximately 4h 13m.
The distance between Otay Mesa and Anaheim is 113 miles. The road distance is 111.8 miles.
The best way to get from Otay Mesa to Anaheim without a car is to tram and bus which takes 3h 47m and costs .
It takes approximately 3h 47m to get from Otay Mesa to Anaheim, including transfers.
Otay Mesa to Anaheim bus services, operated by Limousine Express, depart from San Ysidro station.
Otay Mesa to Anaheim train services, operated by San Diego Metro Transit, depart from Iris Avenue Station.
Otay Mesa to Anaheim bus services, operated by Limousine Express, arrive at Santa Ana station.
What companies run services between Otay Mesa, CA, USA and Anaheim, CA, USA?
You can take a bus from Otay Mesa Rd & Cactus Rd to Ball-Ox via Iris Avenue Transit Center, San Ysidro Transit Center, San Ysidro, Santa Ana, and Santa Ana-Santiago in around 4h 6m.
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Iris Avenue Station to Old Town Station
- Ave. Duration
- 50 min
- Frequency
- Every 20 minutes
- Website
- MTS
- Schedules at
- MTS Schedules
Tram from Iris Avenue Station to America Plaza Station
- Ave. Duration
- 38 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–14
- Website
- MTS
- Schedules at
- MTS Schedules
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Fullerton Amtrak Station
- Ave. Duration
- 2h 19m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Diego to Anaheim Regional Transportation Intermodal Center
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $14–22
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from San Diego to Anaheim Regional Transportation Intermodal Center
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $16–25
- Website
- Greyhound
Bus from San Ysidro to Santa Ana
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $18–28
- Website
- Greyhound
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from San Ysidro to Santa Ana
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Santa Ana-Santiago to Ball-Ox
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Adult One-way
- $2
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Booking & Getting There
Otay Mesa to Anaheim train services, operated by San Diego Metro Transit, arrive at America Plaza Station.
Yes, the driving distance between Otay Mesa to Anaheim is 112 miles. It takes approximately 2h to drive from Otay Mesa to Anaheim.
There are 1333+ hotels available in Anaheim.























