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How to get fromOtay Mesa to Anaheimby bus (Greyhound), tram, train, or car

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There are 4 ways to get from Otay Mesa to Anaheim by bus (Greyhound), tram, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, line 83 bus

    best
    1. Take the bus from San Ysidro to Santa Anabus bus Lxus 3126 / ...
    2. Take the bus from Santa Ana-Santiago to Ball-Oxbus bus 83
    4h 6m
    $22–47
  2. Drive 111.1 mi

    cheapest
    1. Drive from Otay Mesa to Anaheimcar car 111.1 mi
    2h
    $21–30
  3. Tram, train

    1. Take the tram from Iris Avenue Station to America Plaza Stationtram tram Blue
    2. Take the train from San Diego to Fullerton Amtrak Stationtrain train Pacific Surfliner
    4h 11m
    $34–89
  4. Line 929 bus, bus

    1. Take the bus from Iris Avenue Transit Center to 12th & Imperial Transit Centerbus bus 929 / ...
    2. Take the bus from San Diego to Anaheimbus bus Tijuana
    4h 44m
    $24–40

Otay Mesa to Anaheim by bus

Calendar70Weekly Buses
Duration4h 6mAverage Duration
Ticket$22Cheapest Price
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Questions & Answers

What companies run services between Otay Mesa, CA, USA and Anaheim, CA, USA?

You can take a bus from Otay Mesa Rd & Cactus Rd to Ball-Ox via Iris Avenue Transit Center, San Ysidro Transit Center, San Ysidro, Santa Ana, and Santa Ana-Santiago in around 4h 6m.

Bus operators

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Need to know: Greyhound

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