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How to get fromOtay Mesa to Desert Hot Springsby train (Amtrak), train, bus, car, bus (Amtrak), or bus (Greyhound, Flixbus)

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There are 5 ways to get from Otay Mesa to Desert Hot Springs by train (Amtrak), train, bus, car, bus (Amtrak), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from San Diego to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to Palm Springs Stationtrain train Texas Eagle / ...
    8h 36m
    $104–214

  2. Drive 139.6 mi

    cheapest
    1. Drive from Otay Mesa to Desert Hot Springscar car 139.6 mi
    2h 31m
    $26–37

  3. Train, bus (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train Pacific Surfliner
    2. Take the bus from Fullerton Amtrak Station to Palm Springs Airport Amtrak Bus Stopbus bus Amtrak Thruway Connecting Service
    8h 45m
    $66–135

  4. Bus

    1. Take the bus from Otay Mesa Transit Center to India St & C Stbus bus 225
    2. Take the bus from San Diego to Fullerton Amtrak Stationbus bus
    3. Take the bus from Fullerton Amtrak Station to Palm Springs Airport Amtrak Bus Stopbus bus
    9h 49m
    $66–106

  5. Bus via El Centro

    1. Take the bus from San Ysidro Bus Terminal to El Centro Bus Stopbus bus Greyhound US0851S
    2. Take the bus from El Centro Bus Stop to Indio Bus Stationbus bus Greyhound US0850
    10h 17m
    $38–77

Otay Mesa to Desert Hot Springs by bus, tram, train, and foot (Amtrak)

Calendar14Weekly Services
Duration8h 45mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Otay Mesa to Desert Hot Springs.ExpandLaunch map view
  • Distance: 257.7 mi
  • Duration: 8h 36m

What companies run services between Otay Mesa, CA, USA and Desert Hot Springs, CA, USA?

You can take a bus from Otay Mesa Rd & Cactus Rd to Desert Hot Springs via Iris Avenue Transit Center, Iris Avenue Station, America Plaza Station, San Diego, Los Angeles, and Palm Springs Station in around 8h 36m. Alternatively, you can take a bus from Otay Mesa Rd & Cactus Rd to Palm at First St via Otay Mesa Transit Center, India St & C St, San Diego, Fullerton Amtrak Station, Palm Springs Airport Amtrak Bus Stop, and El Cielo at Kirk Douglas in around 9h 49m.

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