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How to get fromOtay Mesa to East Los Angelesby bus, train (Amtrak), car, tram, plane, or bus (Flixbus)

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There are 5 ways to get from Otay Mesa to East Los Angeles by bus, train (Amtrak), car, tram, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from San Ysidro, CA to East Los Angelesbus bus San Ysidro
    5h
    $44–75

  2. Bus via Old Town Station (Flixbus)

    cheapest
    1. Take the bus from San Diego to Los Angeles Downtownbus bus FlixBus 2006 / ...
    5h 55m
    $22–42

  3. Train (Amtrak)

    1. Take the train from San Diego to Los Angelestrain train Pacific Surfliner
    5h 15m
    $42–108

  4. Drive 131.2 mi

    1. Drive from Otay Mesa to East Los Angelescar car 131.2 mi
    2h 19m
    $24–35

  5. Line 905 bus, tram, fly

    1. Take the bus from Otay Mesa Rd & Cactus Rd to Iris Avenue Transit Centerbus bus
    2. Take the tram from Iris Avenue Station to America Plaza Stationtram tram
    3. Fly from San Diego International Airport (SAN) to Los Angeles International Airport (LAX)plane plane SAN - LAX
    4. Take the tram from Little Tokyo / Arts District Station to Maravilla Stationtram tram
    4h 53m
    $176–589

Otay Mesa to East Los Angeles by bus

Calendar7Weekly Buses
Duration5hAverage Duration
Ticket$44Cheapest Price
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Questions & Answers

Map of how to get from Otay Mesa to East Los Angeles.ExpandLaunch map view
  • Distance: 148.5 mi
  • Duration: 5h

What companies run services between Otay Mesa, CA, USA and East Los Angeles, CA, USA?

Tufesa operates a bus from San Ysidro, CA to East Los Angeles once daily. Tickets cost $40–65 and the journey takes 3h 15m. Alternatively, Amtrak operates a train from San Diego to Los Angeles hourly. Tickets cost $35–85 and the journey takes 2h 56m.

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