Rome2Rio

How to get fromOtay Mesa to Las Vegasby tram, plane, bus, car, or bus (Flixbus)

Find Transport to Las Vegas

See all options

There are 4 ways to get from Otay Mesa to Las Vegas by tram, plane, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Tram, fly

    best
    1. Take the tram from Iris Avenue Station to America Plaza Stationtram tram
    2. Fly from San Diego International Airport (SAN) to Harry Reid International Airport (LAS)plane plane SAN - LAS
    3h 58m
    $100–578

  2. Drive 345.5 mi

    cheapest
    1. Drive from Otay Mesa to Las Vegascar car 345.5 mi
    5h 43m
    $64–92

  3. Bus

    1. Take the bus from San Ysidro, CA to Las Vegasbus bus San Ysidro
    9h 25m
    $82–115

  4. Bus via Las Vegas, Gilespie Street (South Strip Transit Terminal) (Flixbus)

    1. Take the bus from San Ysidro Bus Terminal to Las Vegas Stripbus bus FlixBus 2037
    12h 19m
    $74–134

Otay Mesa to Las Vegas by bus and tram

Calendar14Weekly Services
Duration9h 25mAverage Duration
Ticket$82Cheapest Price
See schedules

Questions & Answers

Map of how to get from Otay Mesa to Las Vegas.ExpandLaunch map view
  • Distance: 283.6 mi
  • Duration: 3h 58m

What companies run services between Otay Mesa, CA, USA and Las Vegas, NV, USA?

Tufesa operates a bus from San Ysidro, CA to Las Vegas twice daily. Tickets cost $80–110 and the journey takes 8h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides