There are 5 ways to get from Otay Mesa to Los Angeles by bus, train (Amtrak), car, tram, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from San Ysidro, CA to Downtown Los Angelesbus San Ysidro
4h 45m$44–75Drive 136 mi
cheapest- Drive from Otay Mesa to Los Angelescar 136 mi
2h 24m$25–36Train (Amtrak)
- Take the train from San Diego to Los Angelestrain Pacific Surfliner
4h 48m$44–104Tram, fly
- Take the tram from Iris Avenue Station to America Plaza Stationtram
- Fly from San Diego International Airport (SAN) to Los Angeles International Airport (LAX)plane SAN - LAX
4h 18m$174–687Line 929 bus, bus
- Take the bus from Iris Avenue Transit Center to 12th & Imperial Transit Centerbus 929 / ...
- Take the bus from San Diego to Los Angeles Union Stationbus Tijuana
5h 29m$28–50
Otay Mesa to Los Angeles by bus
Questions & Answers
The cheapest way to get from Otay Mesa to Los Angeles is to drive which costs $24 - $40 and takes 2h 24m.
The fastest way to get from Otay Mesa to Los Angeles is to drive which takes 2h 24m and costs $24 - $40.
No, there is no direct bus from Otay Mesa to Los Angeles. However, there are services departing from Otay Mesa Rd & Cactus Rd and arriving at Downtown Los Angeles via Iris Avenue Transit Center and San Ysidro, CA. The journey, including transfers, takes approximately 4h 45m.
No, there is no direct train from Otay Mesa station to Los Angeles. However, there are services departing from Iris Avenue Station and arriving at Los Angeles via San Diego. The journey, including transfers, takes approximately 4h 48m.
The distance between Otay Mesa and Los Angeles is 144 miles. The road distance is 136.8 miles.
The best way to get from Otay Mesa to Los Angeles without a car is to bus which takes 4h 45m and costs $40 - $75.
It takes approximately 4h 45m to get from Otay Mesa to Los Angeles, including transfers.
Otay Mesa to Los Angeles bus services, operated by Tufesa, depart from San Ysidro, CA station.
Otay Mesa to Los Angeles train services, operated by Amtrak, depart from San Diego station.
The best way to get from Otay Mesa to Los Angeles is to bus which takes 4h 45m and costs $40 - $75. Alternatively, you can train, which costs $40 - $110 and takes 4h 48m.
What companies run services between Otay Mesa, CA, USA and Los Angeles, CA, USA?
Tufesa operates a bus from San Ysidro, CA to Downtown Los Angeles 3 times a day. Tickets cost $40–65 and the journey takes 3h. Alternatively, Amtrak operates a train from San Diego to Los Angeles hourly. Tickets cost $40–85 and the journey takes 2h 56m.
- Website
- delta.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $24–180
- Website
- united.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $24–180
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Diego to Los Angeles
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
.jpg "Pacific Surfliner interior")
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Tram from Iris Avenue Station to America Plaza Station
- Ave. Duration
- 38 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–14
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- Phone
- +1 833 766 3553
- Website
- tufesainternacional.com
Bus from San Ysidro, CA to Downtown Los Angeles
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $40–65
- Schedules at
- tufesainternacional.com
- Adult One way
- $40–65
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Bus from Iris Avenue Transit Center to 12th & Imperial Transit Center
- Ave. Duration
- 1h 14m
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- One Way - Adult/Youth
- $2–5
- Phone
- +1-800-231-2222
- [email protected]
- Website
- greyhound.com.mx
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $23–40
- Schedules at
- greyhound.com.mx
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More Questions & Answers
Otay Mesa to Los Angeles bus services, operated by Tufesa, arrive at Downtown Los Angeles station.
Otay Mesa to Los Angeles train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Otay Mesa to Los Angeles is 137 miles. It takes approximately 2h 24m to drive from Otay Mesa to Los Angeles.
There are 3347+ hotels available in Los Angeles.