There are 5 ways to get from Otay Mesa to Los Angeles Union Station by tram, bus, train (Amtrak), car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Tram, bus
best- Take the tram from Iris Avenue Station to Old Town Stationtram Blue
- Take the bus from San Diego Greyhound Bus Stop to Los Angeles Union Stationbus Greyhound US0831
4h 47mDrive 135.6 mi
cheapest- Drive from Otay Mesa to Los Angeles Union Stationcar 135.6 mi
2h 23m$25–36Train (Amtrak)
- Take the train from San Diego to Los Angelestrain Pacific Surfliner
4h 53m$40–104Tram, fly
- Take the tram from Iris Avenue Station to America Plaza Stationtram
- Fly from San Diego International Airport (SAN) to Los Angeles International Airport (LAX)plane SAN - LAX
4h 18m$174–587Line 929 bus, bus
- Take the bus from Iris Avenue Transit Center to 12th & Imperial Transit Centerbus 929 / ...
- Take the bus from San Diego to Los Angeles Union Stationbus Tijuana
5h 29m$28–50
San Diego International Airport (SAN) to Los Angeles International Airport (LAX) flights
Questions & Answers
The cheapest way to get from Otay Mesa to Los Angeles Union Station is to drive which costs $24 - $40 and takes 2h 23m.
The fastest way to get from Otay Mesa to Los Angeles Union Station is to drive which takes 2h 23m and costs $24 - $40.
No, there is no direct bus from Otay Mesa to Los Angeles Union Station station. However, there are services departing from Otay Mesa Rd & Cactus Rd and arriving at Los Angeles Union Station via Iris Avenue Transit Center and San Diego. The journey, including transfers, takes approximately 5h 29m.
No, there is no direct train from Otay Mesa station to Los Angeles Union Station. However, there are services departing from Iris Avenue Station and arriving at Los Angeles via San Diego. The journey, including transfers, takes approximately 4h 53m.
The distance between Otay Mesa and Los Angeles Union Station is 143 miles. The road distance is 136.4 miles.
The best way to get from Otay Mesa to Los Angeles Union Station without a car is to tram and bus which takes 4h 47m and costs .
It takes approximately 4h 47m to get from Otay Mesa to Los Angeles Union Station, including transfers.
Otay Mesa to Los Angeles Union Station bus services, operated by San Diego Metro Transit, depart from Iris Avenue Transit Center station.
Otay Mesa to Los Angeles Union Station train services, operated by Amtrak, depart from San Diego station.
The best way to get from Otay Mesa to Los Angeles Union Station is to train which takes 4h 53m and costs $35 - $110. Alternatively, you can line 929 bus and bus, which costs $28 - $50 and takes 5h 29m.
What companies run services between Otay Mesa, CA, USA and Los Angeles Union Station, Los Angeles County, CA, USA?
Amtrak operates a train from San Diego to Los Angeles hourly. Tickets cost $35–85 and the journey takes 2h 56m. Alternatively, you can take a bus from Otay Mesa Rd & Cactus Rd to Los Angeles Union Station via Iris Avenue Transit Center, 12th & Imperial Transit Center, and San Diego in around 5h 29m.
- Website
- delta.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $22–180
- Website
- united.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $22–180
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Iris Avenue Station to Old Town Station
- Ave. Duration
- 50 min
- Frequency
- Every 20 minutes
- Website
- MTS
- Schedules at
- MTS Schedules
Tram from Iris Avenue Station to America Plaza Station
- Ave. Duration
- 38 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–14
- Website
- MTS
- Schedules at
- MTS Schedules
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Los Angeles
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- $35–85
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from San Diego Greyhound Bus Stop to Los Angeles Union Station
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $18–35
- Website
- Greyhound
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Iris Avenue Transit Center to 12th & Imperial Transit Center
- Ave. Duration
- 1h 14m
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Schedules at
- Greyhound Mexico
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More Questions & Answers
Otay Mesa to Los Angeles Union Station bus services, operated by San Diego Metro Transit, arrive at 12th & Imperial Transit Center station.
Otay Mesa to Los Angeles Union Station train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Otay Mesa to Los Angeles Union Station is 136 miles. It takes approximately 2h 23m to drive from Otay Mesa to Los Angeles Union Station.
There are 2687+ hotels available in Los Angeles Union Station.
















