There are 3 ways to get from Otay Mesa to Mission Viejo by tram, train, bus (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Tram, train
best- Take the tram from Iris Avenue Station to America Plaza Stationtram Blue
- Take the train from San Diego to San Juan Capistrano Amtrak Stationtrain Pacific Surfliner
4h 18m$28–71Drive 89.3 mi
cheapest- Drive from Otay Mesa to Mission Viejocar 89.3 mi
1h 35m$17–24Bus
- Take the bus from Otay Mesa Transit Center to India St & C Stbus 225
- Take the bus from San Diego to Irvinebus Amtrak Thruway Connecting Service
5h 48m$34–52
Otay Mesa to Mission Viejo by bus, tram, and train
Questions & Answers
The cheapest way to get from Otay Mesa to Mission Viejo is to drive which costs $16 - $24 and takes 1h 35m.
The fastest way to get from Otay Mesa to Mission Viejo is to drive which takes 1h 35m and costs $16 - $24.
No, there is no direct bus from Otay Mesa to Mission Viejo. However, there are services departing from Otay Mesa Rd & Cactus Rd and arriving at Jeronimo-Montilla via Otay Mesa Transit Center, San Diego and Irvine Station-Dock 5. The journey, including transfers, takes approximately 5h 48m.
No, there is no direct train from Otay Mesa station to Mission Viejo station. However, there are services departing from Iris Avenue Station and arriving at San Juan Capistrano Amtrak Station via San Diego. The journey, including transfers, takes approximately 4h 18m.
The distance between Otay Mesa and Mission Viejo is 97 miles. The road distance is 89.8 miles.
The best way to get from Otay Mesa to Mission Viejo without a car is to tram and train which takes 4h 18m and costs $28 - $75.
It takes approximately 4h 18m to get from Otay Mesa to Mission Viejo, including transfers.
Otay Mesa to Mission Viejo bus services, operated by San Diego Metro Transit, depart from Otay Mesa Transit Center station.
Otay Mesa to Mission Viejo train services, operated by San Diego Metro Transit, depart from Iris Avenue Station.
Otay Mesa to Mission Viejo bus services, operated by San Diego Metro Transit, arrive at India St & C St station.
What companies run services between Otay Mesa, CA, USA and Mission Viejo, CA, USA?
You can take a bus from Otay Mesa Rd & Cactus Rd to Jeronimo-Montilla via Otay Mesa Transit Center, India St & C St, San Diego, Irvine, and Irvine Station-Dock 5 in around 5h 48m.
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Iris Avenue Station to America Plaza Station
- Ave. Duration
- 38 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–14
- Website
- MTS
- Schedules at
- MTS Schedules
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to San Juan Capistrano Amtrak Station
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- $22–50
- Website
- Amtrak
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Otay Mesa Transit Center to India St & C St
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from San Diego to Irvine
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- Amtrak
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Otay Mesa to Mission Viejo train services, operated by San Diego Metro Transit, arrive at America Plaza Station.
Yes, the driving distance between Otay Mesa to Mission Viejo is 90 miles. It takes approximately 1h 35m to drive from Otay Mesa to Mission Viejo.
There are 892+ hotels available in Mission Viejo.









