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How to get fromOtay Mesa to Ontarioby bus, train (Amtrak), car, tram, or train

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There are 5 ways to get from Otay Mesa to Ontario by bus, train (Amtrak), car, tram, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from San Ysidro, CA to 285 S East End Ave - Pomonabus bus San Ysidro
    6h 25m
    $52–88

  2. Drive 127.4 mi

    cheapest
    1. Drive from Otay Mesa to Ontariocar car 127.4 mi
    2h 10m
    $24–34

  3. Train (Amtrak)

    1. Take the train from San Diego to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to Ontario Amtraktrain train Texas Eagle / ...
    6h 42m
    $56–129

  4. Tram, bus, line 61 bus

    1. Take the tram from Iris Avenue Station to UCSD Health La Jolla Stationtram tram
    2. Take the bus from San Diego to San Bernardino Downtown Transit Centerbus bus
    3. Take the bus from Fontana Metrolink Transit Center to Holt @ Lemonbus bus 61
    7h 16m
    $24–52

  5. Tram, train, line 59 bus, line 286 bus, line 61 bus

    1. Take the tram from Iris Avenue Station to Santa Fe Depottram tram
    2. Take the train from San Diego to Santa Anatrain train
    3. Take the bus from The Depot At Santa Ana Dock 3 to Ring-Brea Mallbus bus 59
    4. Take the bus from Brea Mall to Pomona Transit Centerbus bus 286
    5. Take the bus from Pomona Transit Center to Holt @ Palmbus bus 61
    7h 37m

Otay Mesa to Ontario by bus

Calendar14Weekly Buses
Duration6h 25mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

Map of how to get from Otay Mesa to Ontario.ExpandLaunch map view
  • Distance: 183.5 mi
  • Duration: 6h 25m

What companies run services between Otay Mesa, CA, USA and Ontario, CA, USA?

Tufesa operates a bus from San Ysidro, CA to 285 S East End Ave - Pomona twice daily. Tickets cost $45–70 and the journey takes 3h 30m. Alternatively, you can take a bus from Otay Mesa Rd & Cactus Rd to Ontario Amtrak via Iris Avenue Transit Center, Iris Avenue Station, America Plaza Station, San Diego, and Los Angeles in around 6h 42m.

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