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How to get fromOtay Mesa to Renoby tram, plane, bus (Greyhound), train (Amtrak), car, or bus (Amtrak)

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There are 5 ways to get from Otay Mesa to Reno by tram, plane, bus (Greyhound), train (Amtrak), car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Tram, fly

    best
    1. Take the tram from Iris Avenue Station to America Plaza Stationtram tram
    2. Fly from San Diego International Airport (SAN) to Reno/Tahoe International Airport (RNO)plane plane SAN - RNO
    3h 57m
    $206–324

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from San Ysidro Bus Terminal to Sacramento Bus Stationbus bus Greyhound US0831
    2. Take the bus from Sacramento Bus Station to Reno Amtrakbus bus Greyhound US0870
    18h 35m
    $102–205

  3. Train (Amtrak)

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to Sacramentotrain train
    3. Take the train from Sacramento to Renotrain train
    25h 50m
    $270–574

  4. Drive 569 mi

    1. Drive from Otay Mesa to Renocar car 569 mi
    10h 23m
    $104–150

  5. Bus via Stockton

    1. Take the bus from Cross Border Xpress to Stocktonbus bus 1
    2. Take the bus from Stockton to Sacramentobus bus
    3. Take the bus from Sacramento to Renobus bus
    21h 9m
    $152–250

Otay Mesa to Reno by bus and tram (Greyhound)

Calendar7Weekly Services
Duration18h 35mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Otay Mesa to Reno.ExpandLaunch map view
  • Distance: 510.7 mi
  • Duration: 3h 57m

What companies run services between Otay Mesa, CA, USA and Reno, NV, USA?

You can take a bus from Otay Mesa Rd & Cactus Rd to Reno Amtrak via Iris Avenue Transit Center, Iris Avenue Station, San Ysidro Station, San Ysidro Bus Terminal, and Sacramento Bus Station in around 18h 35m. Alternatively, you can take a bus from Otay Mesa Rd & Cactus Rd to Reno via Iris Avenue Transit Center, Iris Avenue Station, America Plaza Station, San Diego, Los Angeles, and Sacramento in around 25h 50m.

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Need to know: Greyhound

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