There are 5 ways to get from Otay Mesa to Van Nuys by bus, train (Amtrak), car, tram, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Cross Border Xpress to Pacoima - San Fernandobus 1
4h 12m$50–69Bus via Old Town Station (Flixbus)
cheapest- Take the bus from San Diego to Los Angeles Downtownbus FlixBus 2006 / ...
6h 33m$26–44Train (Amtrak)
- Take the train from San Diego to Van Nuystrain Pacific Surfliner
5h 38m$50–119Drive 152.3 mi
- Drive from Otay Mesa to Van Nuyscar 152.3 mi
2h 45m$28–41Line 905 bus, tram, fly
- Take the bus from Otay Mesa Rd & Cactus Rd to Iris Avenue Transit Centerbus
- Take the tram from Iris Avenue Station to America Plaza Stationtram
- Fly from San Diego International Airport (SAN) to Los Angeles International Airport (LAX)plane SAN - LAX
4h 41m$174–687
Otay Mesa to Van Nuys by bus, tram, and train (Amtrak)
Questions & Answers
The cheapest way to get from Otay Mesa to Van Nuys is to bus via Old Town Station which costs $25 - $45 and takes 6h 33m.
The fastest way to get from Otay Mesa to Van Nuys is to drive which takes 2h 45m and costs $27 - $40.
No, there is no direct bus from Otay Mesa to Van Nuys. However, there are services departing from Cross Border Xpress and arriving at Van Nuys / Victory via Van Nuys / Laurel Canyon. The journey, including transfers, takes approximately 4h 12m.
No, there is no direct train from Otay Mesa station to Van Nuys. However, there are services departing from Iris Avenue Station and arriving at Van Nuys via San Diego. The journey, including transfers, takes approximately 5h 38m.
The distance between Otay Mesa and Van Nuys is 166 miles. The road distance is 153.2 miles.
The best way to get from Otay Mesa to Van Nuys without a car is to bus which takes 4h 12m and costs $50 - $70.
It takes approximately 4h 12m to get from Otay Mesa to Van Nuys, including transfers.
Otay Mesa to Van Nuys bus services, operated by Limousine Express, depart from Cross Border Xpress station.
Otay Mesa to Van Nuys train services, operated by Amtrak, depart from San Diego station.
The best way to get from Otay Mesa to Van Nuys is to bus which takes 4h 12m and costs $50 - $70. Alternatively, you can train, which costs $45 - $120 and takes 5h 38m.
What companies run services between Otay Mesa, CA, USA and Van Nuys, CA, USA?
Limousine Express operates a bus from Cross Border Xpress to Pacoima - San Fernando twice daily. Tickets cost $35–50 and the journey takes 3h 37m. Alternatively, Amtrak operates a train from San Diego to Van Nuys 5 times a day. Tickets cost $45–100 and the journey takes 3h 42m.
- Website
- delta.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $24–180
- Website
- united.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $24–180
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Van Nuys
- Ave. Duration
- 3h 42m
- Frequency
- 5 times a day
- Estimated price
- $45–100
- Website
- Amtrak
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Iris Avenue Station to America Plaza Station
- Ave. Duration
- 38 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–14
- Website
- MTS
- Schedules at
- MTS Schedules
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from Cross Border Xpress to Pacoima - San Fernando
- Ave. Duration
- 3h 37m
- Frequency
- Twice daily
- Estimated price
- $35–50
- Website
- Limousine Express
- One Way
- $35–50
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Otay Mesa Rd & Cactus Rd to Iris Avenue Transit Center
- Ave. Duration
- 13 min
- Frequency
- Hourly
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Diego to Los Angeles Downtown
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
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More Questions & Answers
Otay Mesa to Van Nuys bus services, operated by Limousine Express, arrive at Pacoima - San Fernando station.
Otay Mesa to Van Nuys train services, operated by Amtrak, arrive at Van Nuys station.
Yes, the driving distance between Otay Mesa to Van Nuys is 153 miles. It takes approximately 2h 45m to drive from Otay Mesa to Van Nuys.
There are 2305+ hotels available in Van Nuys.














