There are 6 ways to get from Otranto to Palermo by bus, train, plane, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train, fly
best- Take the bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazionebus
- Take the train from Lecce to Brindisitrain
- Fly from Brindisi Airport (BDS) to Palermo Airport (PMO)plane BDS - PMO
6h 50m€56–144Bus, train
- Take the bus from Otranto, Via Orte to Messina - Piazza della Repubblicabus
- Take the train from Messina Centrale to Palermo Centraletrain Re / ...
12h 29m€61–99Bus, train, ferry
- Take the bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazionebus 101 / ...
- Take the train from Lecce to Sibaritrain Ic
- Take the train from Sibari to Paolatrain Fr
- Take the train from Paola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
13h 51mDrive, car ferry
- Drive from Otranto to Villa S. Giovannicar
- Take the car ferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Palermocar
9h 30m€131–201Bus
- Take the bus from Otranto - Stazione FSE to Lecce - City Terminalbus 101 / ...
- Take the bus from Lecce to Palermobus N595
15h 27m€68–114Bus via Tarsia
- Take the bus from Otranto - Stazione FSE to Lecce - City Terminalbus 101 / ...
- Take the bus from Lecce to Tarsia A3bus
- Take the bus from Tarsia A3 to Palermo Piazza Cairolibus
20h 54m
Otranto to Palermo by bus and train
Questions & Answers
The cheapest way to get from Otranto to Palermo is to bus and train which costs €60 - €100 and takes 12h 29m.
The fastest way to get from Otranto to Palermo is to bus and train and fly which takes 6h 50m and costs €55 - €150.
No, there is no direct bus from Otranto to Palermo. However, there are services departing from Otranto - Stazione FSE and arriving at Palermo via Lecce. The journey, including transfers, takes approximately 15h 27m.
The distance between Otranto and Palermo is 625 km.
The best way to get from Otranto to Palermo without a car is to bus and train which takes 12h 29m and costs €60 - €100.
It takes approximately 6h 50m to get from Otranto to Palermo, including transfers.
Otranto to Palermo bus services, operated by Salento in bus, depart from Otranto - Stazione FSE station.
Otranto to Palermo bus services, operated by Salento in bus, arrive at Lecce - City Terminal station.
Book your Otranto to Palermo bus tickets online with Omio.
There are 6390+ hotels available in Palermo.
What companies run services between Otranto, Apulia, Italy and Palermo, Italy?
You can take a bus from Otranto - Stazione FSE to Palermo via Lecce in around 15h 27m.
- Website
- ita-airways.com
Flights from Brindisi Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- €90–130
- Website
- ryanair.com
Flights from Brindisi Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Tuesday and Saturday
- Estimated price
- €45–110
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Lecce to Brindisi
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- €5–12
- Schedules at
- trenitalia.com
Train from Sibari to Paola
- Ave. Duration
- 48 min
- Frequency
- 3 times a day
- Estimated price
- €11–22
- Schedules at
- trenitalia.com
Train from Paola to Villa S.Giovanni
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €24–50
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lecce to Brindisi
- Ave. Duration
- 30 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–8
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
Train from Paola to Villa S.Giovanni
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €20–35
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Lecce to Brindisi
- Ave. Duration
- 28 min
- Frequency
- Every 3 hours
- Estimated price
- €4–9
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
Train from Lecce to Sibari
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- €24–55
- Website
- https://www.trenitalia.com/en.html
Train from Paola to Villa S.Giovanni
- Ave. Duration
- 3h 16m
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Paola to Villa S.Giovanni
- Ave. Duration
- 1h 49m
- Frequency
- 4 times a day
- Estimated price
- €20–40
- Website
- https://www.italotreno.it/en
- Phone
- +39 800 242 815, 344/2274620
- [email protected]
- Website
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazione
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazione
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - City Terminal
- Ave. Duration
- 1h 42m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - City Terminal
- Ave. Duration
- 1h 42m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
- Phone
- +39 0912742800
- [email protected]
- Website
- saistrasporti.it
Bus from Otranto, Via Orte to Messina - Piazza della Repubblica
- Ave. Duration
- 8h 25m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- https://saistrasporti.it/en-US
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Lecce to Palermo
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- €65–110
- Website
- https://www.flixbus.co.uk
- Phone
- +390981 500331
- [email protected]
- Website
- saj.it
Bus from Lecce to Tarsia A3
- Ave. Duration
- 3h 56m
- Frequency
- 6 times a week
- Estimated price
- €22–45
- Schedules at
- saj.it
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Tarsia A3 to Palermo Piazza Cairoli
- Ave. Duration
- 13h 16m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
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