There are 6 ways to get from Otranto to Palermo by bus, train, plane, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train, fly
best- Take the bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazionebus
- Take the train from Lecce to Brindisitrain
- Fly from Brindisi Airport (BDS) to Palermo Airport (PMO)plane BDS - PMO
6h 49m€61–154Bus via Messina
cheapest- Take the bus from Otranto, Via Orte to Messina - Piazza della Repubblicabus
- Take the bus from Messina Piazza della Repubblica to Palermo Via Oretobus Sais Autolinee 8863 / ...
13h€51–67Bus, train, ferry
- Take the bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazionebus 101 / ...
- Take the train from Lecce to Amanteatrain Ic
- Take the train from Amantea to Villa S.Giovannitrain Re
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
13h 22mDrive, car ferry
- Drive from Otranto to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Palermocar
9h 30m€131–201Bus, train
- Take the bus from Otranto - Stazione FSE to Lecce - Viale Gallipolibus 101 / ...
- Take the train from Lecce to Lamezia Terme C.train Ic
- Take the train from Lamezia Terme C. to Palermo Centraletrain Ic
14h 40m€74–161Bus
- Take the bus from Otranto - Stazione FSE to Lecce - City Terminalbus 101 / ...
- Take the bus from Lecce to Palermobus N595
15h 27m€63–104
Brindisi Airport (BDS) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Otranto to Palermo is to bus via Messina which costs €50 - €70 and takes 13h.
The fastest way to get from Otranto to Palermo is to bus and train and fly which takes 6h 49m and costs €60 - €160.
No, there is no direct bus from Otranto to Palermo. However, there are services departing from Otranto, Via Orte and arriving at John Lennon 100 via Messina Piazza della Repubblica and Regione Siciliana Oreto. The journey, including transfers, takes approximately 13h.
The distance between Otranto and Palermo is 625 km.
The best way to get from Otranto to Palermo without a car is to bus via Messina which takes 13h and costs €50 - €70.
It takes approximately 6h 49m to get from Otranto to Palermo, including transfers.
Otranto to Palermo bus services, operated by Salento in bus, depart from Otranto - Stazione FSE station.
Otranto to Palermo bus services, operated by Salento in bus, arrive at Lecce - City Terminal station.
Book your Otranto to Palermo bus tickets online with Omio.
There are 6395+ hotels available in Palermo.
What companies run services between Otranto, Apulia, Italy and Palermo, Italy?
You can take a bus from Otranto, Via Orte to John Lennon 100 via Messina - Piazza della Repubblica, Messina Piazza della Repubblica, Palermo Via Oreto, and Regione Siciliana Oreto in around 13h.
- Website
- ita-airways.com
Flights from Brindisi Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- €90–130
- Website
- ryanair.com
Flights from Brindisi Airport to Palermo Airport
- Ave. Duration
- 1h 10m
- When
- Tuesday and Saturday
- Estimated price
- €45–120
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Lecce to Brindisi
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €5–12
- Schedules at
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lecce to Brindisi
- Ave. Duration
- 30 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–8
- Website
- Trenitalia
Train from Amantea to Villa S.Giovanni
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- €17–28
- Website
- Trenitalia
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Lecce to Brindisi
- Ave. Duration
- 23 min
- Frequency
- Every 3 hours
- Estimated price
- €4–9
- Website
- Trenitalia Intercity
Train from Lecce to Amantea
- Ave. Duration
- 4h 14m
- Frequency
- Twice daily
- Estimated price
- €35–75
- Website
- Trenitalia Intercity
Train from Amantea to Villa S.Giovanni
- Ave. Duration
- 4h 5m
- Frequency
- Hourly
- Estimated price
- €14–30
- Website
- Trenitalia Intercity
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 4m
- Frequency
- 4 times a day
- Estimated price
- €23–50
- Website
- Trenitalia Intercity
Train from Lecce to Lamezia Terme C.
- Ave. Duration
- 4h 36m
- Frequency
- Twice daily
- Estimated price
- €35–80
- Website
- Trenitalia Intercity
Train from Lamezia Terme C. to Palermo Centrale
- Ave. Duration
- 5h 56m
- Frequency
- Twice daily
- Estimated price
- €35–75
- Website
- Trenitalia Intercity
- Phone
- +39 800 242 815, 344/2274620
- [email protected]
- Website
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazione
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - Camera di Commercio/Stazione
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - Viale Gallipoli
- Ave. Duration
- 1h 37m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
Bus from Otranto - Stazione FSE to Lecce - City Terminal
- Ave. Duration
- 1h 42m
- Frequency
- Every 2 hours
- Estimated price
- €2–4
- Schedules at
- provincia.le.it
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Otranto, Via Orte to Messina - Piazza della Repubblica
- Ave. Duration
- 8h 25m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- SAIS Transporti
- Phone
- 800 21 10 20
- [email protected]
- Website
- SAIS Autolinee
Bus from Messina Piazza della Repubblica to Palermo Via Oreto
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- €12–18
- Schedules at
- SAIS Autolinee
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lecce to Palermo
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- €60–100
- Website
- Flixbus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
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