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How to get fromOttumwa to Greenvilleby bus, plane, bus (Greyhound), train, or car

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There are 7 ways to get from Ottumwa to Greenville by bus, plane, bus (Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Des Moines, fly

    best
    1. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    2. Fly from Des Moines (DSM) to Greenville–Spartanburg International Airport (GSP)plane plane DSM - GSP
    8h 17m
    $296–1,231

  2. Drive 862.9 mi

    cheapest
    1. Drive from Ottumwa to Greenvillecar car 862.9 mi
    16h 13m
    $158–228

  3. Bus

    1. Take the bus from Ottumwa Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    25h 43m
    $203–442

  4. Train, bus via Cary

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    4. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    39h
    $535–1,206

  5. Drive to Burlington Municipal Airport, fly

    1. Drive from Ottumwa to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Greenville–Spartanburg International Airport (GSP)plane plane BRL - GSP
    6h 15m
    $159–665

  6. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    9h 52m
    $221–784

  7. Train, bus

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    28h 1m
    $252–566

Des Moines (DSM) to Greenville–Spartanburg International Airport (GSP) flights

Calendar79Weekly Planes
Duration5h 33mAverage Duration
Ticket$197Cheapest Price
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Questions & Answers

Map of how to get from Ottumwa to Greenville.ExpandLaunch map view
  • Distance: 891.1 mi
  • Duration: 8h 17m

What companies run services between Ottumwa, IA, USA and Greenville, SC, USA?

You can take a bus from Ottumwa Bus Stop to Greenville via Indianapolis Union Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 25h 43m.

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