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How to get fromOttumwa to Knoxvilleby train, taxi, plane, bus, car, shuttle, or bus (Greyhound)

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There are 9 ways to get from Ottumwa to Knoxville by train, taxi, plane, bus, car, shuttle, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi to Quad City International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Ottumwa Amtrak Station to Galesburg Amtrak Stationtrain train
    2. Take the taxi from Galesburg Amtrak Station to SouthPark Mall Sheltertaxi taxi
    3. Fly from Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS)plane plane MLI - TYS
    9h 29m
    $334–948

  2. Drive 721.1 mi

    cheapest
    1. Drive from Ottumwa to Knoxvillecar car 721.1 mi
    12h 40m
    $132–191

  3. Train, bus via Chicago

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    37h 20m
    $414–687

  4. Train, bus

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    40h 17m
    $584–1,087

  5. Drive to Burlington Municipal Airport, fly to Mcghee Tyson Airport

    1. Drive from Ottumwa to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Mcghee Tyson Airport (TYS)plane plane BRL - TYS
    5h 58m
    $189–790

  6. Bus, shuttle to Des Moines, fly to Mcghee Tyson Airport

    1. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    2. Take the bus from Des Moines to Amesbus bus
    3. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    4. Fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS)plane plane DSM - TYS
    10h 19m
    $377–1,412

  7. Bus, shuttle to Des Moines, fly to Nashville, drive

    1. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    2. Take the bus from Des Moines to Amesbus bus
    3. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    4. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    5. Drive from Nashville-Airport-BNA to Knoxvillecar car
    10h 8m
    $242–892

  8. Train, bus via Ossining

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    40h 54m
    $539–1,014

  9. Bus

    1. Take the bus from Ottumwa Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    42h 12m
    $361–602

Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS) flights

Calendar77Weekly Planes
Duration5h 28mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Ottumwa to Knoxville.ExpandLaunch map view
  • Distance: 697.2 mi
  • Duration: 9h 29m

What companies run services between Ottumwa, IA, USA and Knoxville, TN, USA?

You can take a bus from Ottumwa Bus Stop to Knoxville via Indianapolis Union Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 42h 12m.

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