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How to get fromOttumwa to Louisvilleby bus (Greyhound, Amtrak), train, bus, car, shuttle, or plane

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There are 9 ways to get from Ottumwa to Louisville by bus (Greyhound, Amtrak), train, bus, car, shuttle, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Ottumwa Bus Stop to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    10h 35m
    $82–157

  2. Train, bus via Chicago

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    14h 16m
    $173–357

  3. Drive 488.6 mi

    1. Drive from Ottumwa to Louisvillecar car 488.6 mi
    8h 33m
    $90–129

  4. Bus, shuttle to Des Moines, fly

    1. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    2. Take the bus from Des Moines to Amesbus bus
    3. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    4. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    10h 31m
    $254–1,046

  5. Bus via Indianapolis

    1. Take the bus from Ottumwa to Indianapolisbus bus Btw 1402
    2. Take the bus from Indianapolis to Louisville Bus Stationbus bus FlixBus 2512
    11h 9m

  6. Train, bus

    1. Take the train from Ottumwa Amtrak Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    11h 16m

  7. Drive to Burlington Municipal Airport, fly

    1. Drive from Ottumwa to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Louisville International Airport (SDF)plane plane BRL - SDF
    7h 25m
    $95–493

  8. Train to Chicago Midway International Airport, fly

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    9h 46m
    $177–743

  9. Bus, bus to The Eastern Iowa Airport, fly

    1. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    2. Take the bus from Des Moines to Iowa Citybus bus
    3. Fly from The Eastern Iowa Airport (CID) to Louisville International Airport (SDF)plane plane CID - SDF
    12h 28m
    $202–1,014

Ottumwa to Louisville by bus

Calendar7Weekly Buses
Duration10h 35mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Ottumwa to Louisville.ExpandLaunch map view
  • Distance: 490.1 mi
  • Duration: 10h 35m

What companies run services between Ottumwa, IA, USA and Louisville, KY, USA?

You can take a bus from Ottumwa Bus Stop to Louisville Bus Station via Indianapolis Union Station in around 10h 35m.

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