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How to get fromOverland Park to Mayo Clinicby bus, shuttle, car, or plane

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There are 4 ways to get from Overland Park to Mayo Clinic by bus, shuttle, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, shuttle

    best
    1. Take the bus from Kansas City to Owatonnabus bus Jefferson Lines 802 / ...
    2. Take a shuttle bus from Owatonna, MN to Rochestershuttle bus S MN Conn
    10h 54m
    $119–198

  2. Drive 410.3 mi

    cheapest
    1. Drive from Overland Park to Mayo Cliniccar car 410.3 mi
    6h 54m
    $75–109

  3. Fly to Rochester

    1. Fly from Kansas City (MCI) to Rochester (RST)plane plane MCI - RST
    6h 58m
    $115–540

  4. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Kansas City (MCI) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCI - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 30m
    $686–1,042

Kansas City (MCI) to Rochester (RST) flights

Calendar44Weekly Planes
Duration4h 27mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Overland Park to Mayo Clinic.ExpandLaunch map view
  • Distance: 434.1 mi
  • Duration: 10h 54m

What companies run services between Overland Park, KS, USA and Mayo Clinic, MN, USA?

Delta, United Airlines, and American Airlines fly from Kansas City (MCI) to Rochester (RST) every 4 hours.

Airlines
Bus operators

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