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How to get fromOwensboro to Buffaloby plane, taxi, bus, car, or train

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There are 7 ways to get from Owensboro to Buffalo by plane, taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Owensboro–Daviess County Regional Airport

    best
    1. Fly from Owensboro–Daviess County Regional Airport (OWB) to Buffalo Niagara International Airport (BUF)plane plane OWB - BUF
    6h
    $126–641

  2. Drive  632.2 mi

    cheapest
    1. Drive from Owensboro to Buffalocar car 632.2 mi
    10h 56m
    $116–167

  3. Taxi, bus

    1. Take the taxi from Owensboro to Dale, INtaxi taxi
    2. Take the bus from Dale, IN to Louisville, KYbus bus
    3. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    14h 7m
    $154–310

  4. Taxi to Evansville, fly

    1. Take the taxi from Owensboro to Evansville (EVV)taxi taxi
    2. Fly from Evansville (EVV) to Buffalo Niagara International Airport (BUF)plane plane EVV - BUF
    6h 45m
    $198–738

  5. Taxi, bus via Akron

    1. Take the taxi from Owensboro to Dale, INtaxi taxi
    2. Take the bus from Dale, IN to Louisville, KYbus bus
    3. Take the bus from Louisville to Akronbus bus
    4. Take the bus from Akron to Buffalobus bus
    14h 37m
    $152–315

  6. Taxi, bus via Columbus

    1. Take the taxi from Owensboro to Dale, INtaxi taxi
    2. Take the bus from Dale, IN to Louisville, KYbus bus
    3. Take the bus from Louisville to Columbusbus bus
    4. Take the bus from Columbus to Buffalobus bus
    15h 15m
    $183–308

  7. Taxi, bus, train

    1. Take the taxi from Owensboro to Dale, INtaxi taxi
    2. Take the bus from Dale, IN - Denny's to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Toledo Bus Stopbus bus
    4. Take the train from Toledo to Buffalo Depew Stationtrain train
    17h 41m
    $235–499

Owensboro–Daviess County Regional Airport (OWB) to Buffalo Niagara International Airport (BUF) flights

Calendar26Weekly Planes
Duration6h 14mAverage Duration
Ticket$110Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Owensboro to Buffalo.ExpandLaunch map view
  • Distance: 583.9 mi
  • Duration: 6h

What companies run services between Owensboro, KY, USA and Buffalo, NY, USA?

United Airlines flies from Owensboro–Daviess County Regional Airport (OWB) to Buffalo Niagara International Airport (BUF) 4 times a day.

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