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How to get fromOxford to Chicagoby car, plane, bus, or train

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There are 7 ways to get from Oxford to Chicago by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Memphis, fly to Chicago Midway International Airport

    best
    1. Drive from Oxford to Memphis-Airport-MEMcar car
    2. Fly from Memphis (MEM) to Chicago Midway International Airport (MDW)plane plane MEM - MDW
    3h 36m
    $89–463

  2. Drive to Memphis, fly to Chicago O'Hare International Airport

    cheapest
    1. Drive from Oxford to Memphis-Airport-MEMcar car
    2. Fly from Memphis (MEM) to Chicago O'Hare International Airport (ORD)plane plane MEM - ORD
    4h 7m
    $74–393

  3. Drive, bus

    1. Drive from Oxford to Memphis Bus Stationcar car
    2. Take the bus from Memphis Bus Station to Chicago Bus Stationbus bus Greyhound US0125
    10h 59m
    $92–178

  4. Drive 581.9 mi

    1. Drive from Oxford to Chicagocar car 581.9 mi
    10h 49m
    $107–154

  5. Drive to Mc Kellar-Sipes Regional Airport, fly to Chicago O'Hare International Airport

    1. Drive from Oxford to Mc Kellar-Sipes Regional Airport (MKL)car car
    2. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Chicago O'Hare International Airport (ORD)plane plane MKL - ORD
    5h 1m
    $191–433

  6. Drive to Birmingham–Shuttlesworth International Airport, fly to Chicago Midway International Airport

    1. Drive from Oxford to Birmingham-Airport-BHMcar car
    2. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Chicago Midway International Airport (MDW)plane plane BHM - MDW
    5h 47m
    $116–504

  7. Drive, bus, train

    1. Drive from Oxford to Memphis Bus Stationcar car
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Chicago Union Stationtrain train
    11h 59m
    $137–293

Memphis (MEM) to Chicago Midway International Airport (MDW) flights

Calendar14Weekly Planes
Duration1h 35mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Oxford to Chicago.ExpandLaunch map view
  • Distance: 560.2 mi
  • Duration: 3h 36m

What companies run services between Oxford, Lafayette County, MS, USA and Chicago, IL, USA?

There is no direct connection from Oxford to Chicago. However, you can drive to Memphis-Airport-MEM airport, fly to Chicago Midway International Airport (MDW), walk to Midway, then take the subway to Harold Washington Library. Alternatively, you can take a vehicle from Oxford to Chicago Bus Station via Memphis Bus Station in around 10h 59m.

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