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How to get fromPaducah to La Crosseby bus, plane, train, car, or bus (Flixbus, Greyhound)

Find Transport to La Crosse

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There are 7 ways to get from Paducah to La Crosse by bus, plane, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Williamson County Regional Airport, fly

    best
    1. Take the bus from Paducah Bus Station to Carbondale Intermodal Stationbus bus
    2. Fly from Williamson County Regional Airport (MWA) to La Crosse (LSE)plane plane MWA - LSE
    8h 1m
    $129–451

  2. Drive  573.6 mi

    cheapest
    1. Drive from Paducah to La Crossecar car 573.6 mi
    10h 54m
    $105–152

  3. Bus, train

    1. Take the bus from Paducah Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    13h 53m
    $340–538

  4. Bus, train via Madison

    1. Take the bus from Paducah Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to La Crossebus bus
    15h 32m
    $250–408

  5. Fly from Barkley Regional Airport

    1. Fly from Barkley Regional Airport (PAH) to La Crosse (LSE)plane plane PAH - LSE
    6h 56m
    $105–424

  6. Drive to Cape Girardeau Municipal Airport, fly

    1. Drive from Paducah to Cape Girardeau Municipal Airport (CGI)car car
    2. Fly from Cape Girardeau Municipal Airport (CGI) to La Crosse (LSE)plane plane CGI - LSE
    10h 40m
    $153–593

  7. Bus

    1. Take the bus from Paducah Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    17h 49m
    $149–225

Williamson County Regional Airport (MWA) to La Crosse (LSE) flights

Calendar10Weekly Planes
Duration6h 16mAverage Duration
Ticket$61Cheapest Price
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Comparing Your Travel Options

Map of how to get from Paducah to La Crosse.ExpandLaunch map view
  • Distance: 533.1 mi
  • Duration: 8h 1m

What companies run services between Paducah, KY, USA and La Crosse, WI, USA?

United Airlines and American Airlines fly from Barkley Regional Airport (PAH) to La Crosse (LSE) once daily. Alternatively, you can take a vehicle from Paducah to La Crosse via Paducah Bus Station, St Louis Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 17h 49m.

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