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How to get fromPaducah to Mayo Clinicby plane, bus, train, car, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Paducah to Mayo Clinic by plane, bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barkley Regional Airport to Minneapolis–Saint Paul International Airport, bus

    best
    1. Fly from Barkley Regional Airport (PAH) to Minneapolis–Saint Paul International Airport (MSP)plane plane PAH - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 15m
    $166–571

  2. Fly Barkley Regional Airport to Rochester

    cheapest
    1. Fly from Barkley Regional Airport (PAH) to Rochester (RST)plane plane PAH - RST
    8h 13m
    $92–451

  3. Bus, train via Madison

    1. Take the bus from Paducah Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    17h 40m
    $265–428

  4. Bus, train

    1. Take the bus from Paducah Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    18h 58m
    $438–688

  5. Drive  620.3 mi

    1. Drive from Paducah to Mayo Cliniccar car 620.3 mi
    11h 4m
    $114–164

  6. Bus to Williamson County Regional Airport, fly to Rochester

    1. Take the bus from Paducah Bus Station to Carbondale Intermodal Stationbus bus
    2. Fly from Williamson County Regional Airport (MWA) to Rochester (RST)plane plane MWA - RST
    9h 2m
    $116–478

  7. Bus to Lambert–St. Louis International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Paducah Bus Station to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Minneapolis–Saint Paul International Airport (MSP)plane plane STL - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 48m
    $168–604

  8. Bus to Nashville, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Paducah Bus Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Minneapolis–Saint Paul International Airport (MSP)plane plane BNA - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 39m
    $182–698

  9. Bus

    1. Take the bus from Paducah Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    19h 57m
    $169–250

Barkley Regional Airport (PAH) to Minneapolis–Saint Paul International Airport (MSP) flights

Calendar27Weekly Planes
Duration7h 15mAverage Duration
Ticket$90Cheapest Price
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Comparing Your Travel Options

Map of how to get from Paducah to Mayo Clinic.ExpandLaunch map view
  • Distance: 679.7 mi
  • Duration: 8h 15m

What companies run services between Paducah, KY, USA and Mayo Clinic, MN, USA?

United Airlines, American Airlines, and Delta fly from Barkley Regional Airport (PAH) to Rochester (RST) 3 times a day. Alternatively, you can take a vehicle from Paducah to Mayo Clinic via Paducah Bus Station, St Louis Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 19h 57m.

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