There are 9 ways to get from Palatine to Lexington by plane, car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Covington, drive
best- Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane ORD - CVG
- Drive from Covington (CVG) to Lexingtoncar
4h 58m$171–782Train to Chicago O'Hare International Airport, fly to Blue Grass Airport
cheapest- Take the train from Palatine to Irving Parktrain
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane ORD - LEX
5h 54m$48–282Train, bus, drive
- Take the train from Palatine to Chicago OTCtrain
- Take the bus from Chicago Union Station to Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
13h 40m$71–90Drive 388.7 mi
- Drive from Palatine to Lexingtoncar 388.7 mi
7h 12m$71–103Fly Chicago O'Hare International Airport to Louisville International Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
5h 6m$90–501Train to Chicago Midway International Airport, fly to Louisville International Airport, drive
- Take the train from Palatine to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane MDW - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
5h 36m$121–732Train to Chicago Midway International Airport, fly to Covington, drive
- Take the train from Palatine to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Covington (CVG)plane MDW - CVG
- Drive from Covington (CVG) to Lexingtoncar
5h 37m$182–333Fly Chicago O'Hare International Airport to Dayton, drive
- Fly from Chicago O'Hare International Airport (ORD) to Dayton (DAY)plane ORD - DAY
- Drive from Dayton-Airport-DAY to Lexingtoncar
6h 1m$68–310Train, bus, drive via Lafayette
- Take the train from Palatine to Chicago OTCtrain
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
- Take the bus from Lafayette Amtrak Station to Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
14h 48m$117–193
Chicago O'Hare International Airport (ORD) to Covington (CVG) flights
Comparing Your Travel Options
The cheapest way to get from Palatine to Lexington is to train and bus and drive which costs $70 - $90 and takes 13h 40m.
The fastest way to get from Palatine to Lexington is to fly and drive which takes 4h 58m and costs $170 - $800.
The distance between Palatine and Lexington is 378 miles. The road distance is 391 miles.
It takes approximately 4h 58m to get from Palatine to Lexington, including transfers.
Lexington is 1h ahead of Palatine. It is currently 3:41 AM in Palatine and 4:41 AM in Lexington.
Yes, the driving distance between Palatine to Lexington is 391 miles. It takes approximately 7h 12m to drive from Palatine to Lexington.
There are 181+ hotels available in Lexington.
What companies run services between Palatine, IL, USA and Lexington, KY, USA?
There is no direct connection from Palatine to Lexington. However, you can take the train to Irving Park, walk to Irving Park-Blue, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Covington (CVG), then drive to Lexington. Alternatively, you can take a train from Palatine to Lexington via Chicago OTC, Madison & Canal, Clinton & Jackson, Chicago Union Station, Louisville, KY, W Broadway @ S 11th, Bardstown @ Eastern Pkwy, S 5th @ W Jefferson, and Middletown Station @ Target in around 13h 40m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Covington
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $65–450
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $70–470
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Dayton
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $35–260
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Covington
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $65–450
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $70–470
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Dayton
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $35–260
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $100–700
Flights from Chicago Midway International Airport to Covington
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $95–650
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Palatine to Chicago OTC
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Metra
- Adult
- $4–6
Train from Palatine to Irving Park
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Metra
- Adult
- $4–6
Train from Palatine to Chicago OTC
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Metra
- Adult
- $4–6
Train from Palatine to Chicago OTC
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Metra
- Adult
- $4–6
Train from Palatine to Chicago OTC
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Metra
- Adult
- $4–6
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $65–110
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Bus from Lafayette Amtrak Station to Louisville, KY
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide






