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How to get fromPalatine to Louisvilleby train, plane, bus, or car

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There are 9 ways to get from Palatine to Louisville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Louisville International Airport

    best
    1. Take the train from Palatine to Irving Parktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 47m
    $72–423

  2. Train, bus

    cheapest
    1. Take the train from Palatine to Chicago OTCtrain train Up-Nw
    2. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    8h 13m
    $53–99

  3. Train, bus via Indianapolis

    1. Take the train from Palatine to Chicago OTCtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    9h 46m
    $90–184

  4. Drive 320.6 mi

    1. Drive from Palatine to Louisvillecar car 320.6 mi
    5h 41m
    $59–85

  5. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 56m
    $119–679

  6. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Palatine to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 18m
    $88–564

  7. Fly Chicago O'Hare International Airport to Evansville, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Evansville (EVV)plane plane ORD - EVV
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    6h 55m
    $106–380

  8. Train, bus via Indianapolis #2

    1. Take the train from Palatine to Chicago OTCtrain train
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus
    3. Take the bus from Indianapolis to Louisville Bus Stationbus bus
    8h 33m

  9. Train, bus via Gary

    1. Take the train from Palatine to Chicago OTCtrain train
    2. Take the train from Millennium Station to Gary Metro Centertrain train Ssl
    3. Take the bus from Gary Bus Station to Louisville Bus Stationbus bus
    8h 38m
    $55–98

Palatine to Louisville by train and bus

Calendar82Weekly Services
Duration8h 13mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

Map of how to get from Palatine to Louisville.ExpandLaunch map view
  • Distance: 321.8 mi
  • Duration: 4h 47m

What companies run services between Palatine, IL, USA and Louisville, KY, USA?

There is no direct connection from Palatine to Louisville. However, you can take the train to Irving Park, walk to Irving Park-Blue, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Louisville International Airport (SDF), walk to Louisville International Airport, then take the line 02 bus to 2nd @ York. Alternatively, you can take a train from Palatine to Louisville Bus Station via Chicago OTC, Madison & Canal, Harrison & Jefferson, and Chicago Bus Station in around 8h 13m.

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