There are 9 ways to get from Palermo Airport (PMO) to Siena by plane, train, ferry, car, train (Trenitalia), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane PMO - FLR
- Take the train from Firenze S.M.N. to Sienatrain
3h 43m€71–193Fly to Bologna Guglielmo Marconi Airport, train
cheapest- Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane PMO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
4h 17m€41–200Ferry, drive
- Take the ferry from Palermo to Civitavecchiaferry
- Drive from Civitavecchia to Sienacar
16h 39m€78–142Train (Trenitalia)
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
17h 5m€134–297Bus
- Take the bus from Palermo to Sienabus N597
18h 10m€106–176Fly to Pisa International Airport, train
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane PMO - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
3h 35m€51–235Fly to Perugia Sant'Egidio Airport, bus
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane PMO - PEG
- Take the bus from Perugia to Sienabus
5h 34m€65–218Train via Chiusi (Trenitalia)
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Chiusi-Chianciano T.train
- Take the train from Chiusi-Chianciano T. to Sienatrain Re
17h 45m€122–251Bus via Florence
- Take the bus from Palermo Piazza Cairoli to Florence Villa Constanza Bus Stationbus
- Take the bus from Stazione Leopolda to Siena-Via Tozzibus 131R / ...
23h 29m
Palermo Airport (PMO) to Siena by train (Trenitalia)
Questions & Answers
The cheapest way to get from Palermo Airport (PMO) to Siena is to fly and train which costs €50 - €240 and takes 3h 35m.
The fastest way to get from Palermo Airport (PMO) to Siena is to fly and train which takes 3h 35m and costs €50 - €240.
No, there is no direct bus from Palermo Airport (PMO) to Siena. However, there are services departing from Palermo Airport Bus Stop and arriving at Siena via Palermo. The journey, including transfers, takes approximately 18h 10m.
No, there is no direct train from Palermo Airport (PMO) to Siena. However, there are services departing from Palermo Aeroporto and arriving at Siena via Palermo Centrale, Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 17h 5m.
The distance between Palermo Airport (PMO) and Siena is 743 km.
The best way to get from Palermo Airport (PMO) to Siena without a car is to train which takes 17h 5m and costs €130 - €300.
It takes approximately 3h 43m to get from Palermo Airport (PMO) to Siena, including transfers.
Palermo Airport (PMO) to Siena bus services, operated by FlixBus, depart from Palermo station.
Palermo Airport (PMO) to Siena train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo Airport (PMO) to Siena is to train which takes 17h 5m and costs €130 - €300. Alternatively, you can bus, which costs €100 - €180 and takes 18h 10m.
What companies run services between Palermo Airport (PMO), Italy and Siena, Italy?
You can take a train from Palermo Aeroporto to Siena via Palermo Centrale, Roma Termini, and Firenze S.M.N. in around 17h 5m. Alternatively, FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €100–170 and the journey takes 16h 20m.
- Website
- ryanair.com
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–200
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €30–160
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €50–200
- Website
- ita-airways.com
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €80–170
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €70–170
- Website
- volotea.com
Flights from Palermo Airport to Florence Peretola Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €35–140
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €80–170
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €70–170
- Website
- flyulendo.com
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €13–110
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 35m
- Frequency
- Every 3 hours
- Estimated price
- €30–55
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €11–18
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- 4 times a day
- Estimated price
- €90–190
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- 4 times a day
- Estimated price
- €90–190
- Website
- Trenitalia Intercity
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- Italo Treno
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Palermo to Siena
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- Flixbus
Bus from Perugia to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €9–15
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Florence Villa Constanza Bus Station
- Ave. Duration
- 19h 39m
- Frequency
- Twice a week
- Website
- Onebus
- Phone
- +39 800 142 424
- [email protected]
- Website
- Autolinee Toscane
Bus from Stazione Leopolda to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- Autolinee Toscane
- Schedules at
- Autolinee Toscane
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Ferry from Palermo to Civitavecchia
- Ave. Duration
- 13h 45m
- Frequency
- 3 times a week
- Estimated price
- €45–90
- Website
- Grandi Navi Veloci
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More Questions & Answers
Palermo Airport (PMO) to Siena bus services, operated by FlixBus, arrive at Siena station.
Palermo Airport (PMO) to Siena train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
There are 2531+ hotels available in Siena.






























