There are 6 ways to get from Palermo (Region) to Brindisi by train, ferry, bus, car, car ferry, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, ferry (Trenitalia)
best- Take the train from Termini Imerese to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Brindisitrain Ic
11h 25mDrive, car ferry
cheapest- Drive from Palermo (Region) to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Brindisicar
8h 16m€125–198Bus
- Take the bus from Vicari to Palermobus
- Take the bus from Palermo Via Tommaso Fazello to Catania Central Bus Stationbus
- Take the bus from Catania, Via D'Amico to Brindisibus
14h 9mBus, fly
- Take the bus from Vicari to Palermobus
- Fly from Palermo Airport (PMO) to Brindisi Airport (BDS)plane PMO - BDS
6h 57mBus, train
- Take the bus from Vicari to Palermobus
- Take the train from Palermo Centrale to Lamezia Terme C.train Ic
- Take the train from Lamezia Terme C. to Brindisitrain Ic
13h 22mBus via Tarsia
- Take the bus from Vicari to Palermobus
- Take the bus from Palermo Piazza Cairoli to Tarsia A3bus
- Take the bus from Tarsia A3 to Brindisibus
20h 55m
Palermo Airport (PMO) to Brindisi Airport (BDS) flights
Comparing Your Travel Options
The cheapest way to get from Palermo (Region) to Brindisi is to drive and car ferry which costs €120 - €200 and takes 8h 16m.
The fastest way to get from Palermo (Region) to Brindisi is to drive and car ferry which takes 8h 16m and costs €120 - €200.
No, there is no direct bus from Palermo (Region) to Brindisi. However, there are services departing from Vicari and arriving at Brindisi via Palermo Via Tommaso Fazello and Catania, Via D'Amico. The journey, including transfers, takes approximately 14h 9m.
The distance between Palermo (Region) and Brindisi is 664 km.
The best way to get from Palermo (Region) to Brindisi without a car is to train and ferry which takes 11h 25m and costs .
It takes approximately 11h 25m to get from Palermo (Region) to Brindisi, including transfers.
Palermo (Region) to Brindisi bus services, operated by Azienda Siciliana Trasporti, depart from Vicari station.
Palermo (Region) to Brindisi bus services, operated by Azienda Siciliana Trasporti, arrive at Palermo station.
There are 1009+ hotels available in Brindisi.
What companies run services between Palermo (Region), Sicily, Italy and Brindisi, Italy?
You can take a bus from Vicari to Brindisi via Palermo, Palermo Via Tommaso Fazello, Catania Central Bus Station, and Catania, Via D'Amico in around 14h 9m.
- Website
- ita-airways.com
Flights from Palermo Airport to Brindisi Airport via Rome
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- €95–140
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Termini Imerese to Messina Centrale
- Ave. Duration
- 2h 29m
- Frequency
- Hourly
- Estimated price
- €22–30
- Website
- Trenitalia
- Phone
- +39 091-6208000
- [email protected]
- Website
- aziendasicilianatrasporti.it
Bus from Vicari to Palermo
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Vicari to Palermo
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Vicari to Palermo
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Vicari to Palermo
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Travelling by boat in Italy
Read the travel guide
Want to know more about Flixbus?
Read the travel guide






