There are 12 ways to get from Palermo to Karlsruhe by plane, train, ferry, car ferry, car, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Frankfurt, train
best- Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane PMO - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
7h 12m€100–270Fly to Milano Malpensa Airport, train
cheapest- Fly from Palermo Airport (PMO) to Milano Malpensa Airport (MXP)plane PMO - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
- Take the train from Lugano to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
11h 26m€63–498Train, ferry
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Milano Centraletrain Fr
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain 12 / ...
20h 45mCar ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Karlsruhecar
26h€223–324Bus
- Take the bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Stationbus
32h 59m€260–370Fly to Stuttgart Airport, train
- Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane PMO - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
6h 26m€90–295Fly to Basel, train
- Fly from Palermo Airport (PMO) to Basel (BSL)plane PMO - BSL
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
7h 20m€76–321Fly to Allgäu Airport, Memmingen, train
- Fly from Palermo Airport (PMO) to Allgäu Airport, Memmingen (FMM)plane PMO - FMM
- Take the train from Memmingen, Bahnhof ZOB to Ulm Hauptbahnhoftrain
- Take the train from Ulm Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
8h 54m€76–327Fly to Hahn, bus, train
- Fly from Palermo Airport (PMO) to Hahn (HHN)plane PMO - HHN
- Take the bus from Hahn to Mainz, Hauptbahnhofbus
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
8h 39m€116–444Fly to Zurich Airport, train
- Fly from Palermo Airport (PMO) to Zurich Airport (ZRH)plane PMO - ZRH
- Take the train from Zürich HB to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
8h 30m€137–344Train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain 12 / ...
22h 1m€257–503Bus via Milan
- Take the bus from Palermo to Milano, Autostazione Lampugnanobus N597
- Take the bus from Milano, Autostazione Lampugnano to Karlsruhe central train stationbus N77
33h 5m€193–290
Palermo Airport (PMO) to Frankfurt (FRA) flights
Comparing Your Travel Options
The cheapest way to get from Palermo to Karlsruhe is to fly and train which costs €75 - €330 and takes 8h 54m.
The fastest way to get from Palermo to Karlsruhe is to fly and train which takes 6h 26m and costs €85 - €300.
Yes, there is a direct bus departing from Palermo Piazza Cairoli and arriving at Karlsruhe Central Bus Station station. Services depart once a week, and operate Wednesday and Saturday. The journey takes approximately 32h 59m.
No, there is no direct train from Palermo to Karlsruhe. However, there are services departing from Palermo Centrale and arriving at Karlsruhe Hauptbahnhof via Roma Termini, Milano Centrale and Basel SBB. The journey, including transfers, takes approximately 22h 1m.
The distance between Palermo and Karlsruhe is 1530 km.
The best way to get from Palermo to Karlsruhe without a car is to train and ferry which takes 20h 45m and costs .
It takes approximately 7h 12m to get from Palermo to Karlsruhe, including transfers.
Palermo to Karlsruhe bus services, operated by Onebus, depart from Palermo Piazza Cairoli station.
Palermo to Karlsruhe train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo to Karlsruhe is to bus which takes 32h 59m and costs €260 - €370. Alternatively, you can train, which costs €250 - €550 and takes 22h 1m.
What companies run services between Palermo, Italy and Karlsruhe, Germany?
Onebus operates a bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Station once a week. Tickets cost €260–370 and the journey takes 32h 59m. Alternatively, you can take a train from Palermo Centrale to Karlsruhe Hauptbahnhof via Roma Termini, Milano Centrale, and Basel SBB in around 22h 1m.
- Website
- ryanair.com
Flights from Palermo Airport to Allgäu Airport, Memmingen
- Ave. Duration
- 2h
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–200
Flights from Palermo Airport to Allgäu Airport, Memmingen via Rome
- Ave. Duration
- 4h 20m
- When
- Friday and Saturday
- Estimated price
- €40–200
Flights from Palermo Airport to Hahn
- Ave. Duration
- 2h 20m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- €85–380
Flights from Palermo Airport to Hahn via Rome
- Ave. Duration
- 4h 20m
- When
- Monday
- Estimated price
- €85–380
Flights from Palermo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €30–290
- Website
- easyjet.com
Flights from Palermo Airport to Basel
- Ave. Duration
- 2h 10m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €35–180
Flights from Palermo Airport to Basel via Nice
- Ave. Duration
- 4h 15m
- When
- Tuesday
- Estimated price
- €35–180
Flights from Palermo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–290
- Website
- ita-airways.com
Flights from Palermo Airport to Frankfurt via Milan Linate
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- €95–200
Flights from Palermo Airport to Stuttgart Airport via Rome
- Ave. Duration
- 3h 55m
- When
- Sunday
- Estimated price
- €65–260
- Website
- lufthansa.com
Flights from Palermo Airport to Frankfurt
- Ave. Duration
- 2h 20m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €100–370
Flights from Palermo Airport to Frankfurt via Munich
- Ave. Duration
- 4h 45m
- When
- Friday
- Estimated price
- €100–370
- Website
- flyulendo.com
Flights from Palermo Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- €9–210
- Website
- eurowings.com
Flights from Palermo Airport to Stuttgart Airport
- Ave. Duration
- 2h 5m
- When
- Wednesday and Saturday
- Estimated price
- €65–260
- Website
- swiss.com
Flights from Palermo Airport to Zurich Airport
- Ave. Duration
- 2h 5m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €90–360
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €12–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Memmingen, Bahnhof ZOB to Ulm Hauptbahnhof
- Ave. Duration
- 31 min
- Frequency
- Twice daily
- Estimated price
- €8–17
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Ulm Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 32m
- Frequency
- Every 4 hours
- Estimated price
- €27–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €11–23
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 22 min
- Frequency
- Hourly
- Estimated price
- €9–20
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 44m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- €24–45
- Website
- Trenitalia Intercity
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 14h 53m
- Frequency
- 3 times a week
- Estimated price
- €130–240
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- 4 times a day
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 8h 48m
- Frequency
- Every 3 hours
- Estimated price
- €160–280
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Villa S.Giovanni to Milano Centrale
- Ave. Duration
- 9h 59m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 21m
- Frequency
- Every 2 hours
- Estimated price
- €75–130
- Website
- Trenitalia Eurocity
- 1st Class
- €90–130
- 2nd Class
- €75–110
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 43m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 43m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 43m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 53m
- Frequency
- 4 times a day
- Estimated price
- €55–110
- Website
- Trenitalia Eurocity
- 1st Class
- €75–110
- 2nd Class
- €55–80
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 43m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 21m
- Frequency
- Every 2 hours
- Estimated price
- €75–130
- Website
- Trenitalia Eurocity
- 1st Class
- €90–130
- 2nd Class
- €75–110
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 43m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 28m
- Frequency
- Once daily
- Estimated price
- €9–13
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Memmingen, Bahnhof ZOB to Ulm Hauptbahnhof
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–9
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 57 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–10
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 6m
- Frequency
- 5 times a week
- Estimated price
- €13–19
- Schedules at
- Süwex
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 42 min
- Frequency
- Twice daily
- Estimated price
- €16
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 6131 4975 022
- [email protected]
- Website
- dbregiobus-mitte.de
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once a week
- Estimated price
- €13–19
- Schedules at
- dbregiobus-mitte.de
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €29–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 53m
- Frequency
- Every 3 hours
- Estimated price
- €80–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- Trenord
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 56m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Station
- Ave. Duration
- 32h 59m
- Frequency
- Once a week
- Estimated price
- €260–370
- Website
- Onebus
- Phone
- +49 (0) 6543 5019-400
- [email protected]
- Website
- Bohr
Bus from Hahn to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €14–16
- Schedules at
- Bohr
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Palermo to Milano, Autostazione Lampugnano
- Ave. Duration
- 22h 20m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Karlsruhe central train station
- Ave. Duration
- 9h 45m
- Frequency
- Twice daily
- Estimated price
- €50–80
- Website
- Flixbus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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Booking & Getting There
Palermo to Karlsruhe bus services, operated by Onebus, arrive at Karlsruhe Central Bus Station.
Palermo to Karlsruhe train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Palermo to Karlsruhe train tickets online with Omio.
Book your Palermo to Karlsruhe bus tickets online with Omio.
There are 897+ hotels available in Karlsruhe.


































































