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How to get fromPalermo to Karlsruheby plane, train, train (Trenitalia), car ferry, car, or bus

Find Transport to Karlsruhe

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There are 11 ways to get from Palermo to Karlsruhe by plane, train, train (Trenitalia), car ferry, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Frankfurt, train

    best
    1. Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane plane PMO - FRA
    2. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 12m
    €98–270

  2. Fly to Allgäu Airport, Memmingen, train

    cheapest
    1. Fly from Palermo Airport (PMO) to Allgäu Airport, Memmingen (FMM)plane plane PMO - FMM
    2. Take the train from Memmingen, Bahnhof ZOB to Ulm Hauptbahnhoftrain train
    3. Take the train from Ulm Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    8h 54m
    €80–360

  3. Train

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Milano Centraletrain train
    3. Take the train from Milano Centrale to Karlsruhe Hbftrain train Ec
    21h 54m
    €270–447

  4. Car ferry, drive

    1. Take the carferry from Port of Palermo to Port of Genoacarferry car ferry
    2. Drive from Port of Genoa to Karlsruhecar car
    26h
    €223–324

  5. Bus

    1. Take the bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Stationbus bus
    32h 59m
    €260–370

  6. Fly to Stuttgart Airport, train

    1. Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane plane PMO - STR
    2. Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    6h 28m
    €91–354

  7. Fly to Basel, train

    1. Fly from Palermo Airport (PMO) to Basel (BSL)plane plane PMO - BSL
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    7h 21m
    €85–416

  8. Fly to Zurich Airport, train

    1. Fly from Palermo Airport (PMO) to Zurich Airport (ZRH)plane plane PMO - ZRH
    2. Take the train from Zürich HB to Basel SBBtrain train
    3. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    8h 31m
    €141–439

  9. Fly to Hahn, bus, train

    1. Fly from Palermo Airport (PMO) to Hahn (HHN)plane plane PMO - HHN
    2. Take the bus from Hahn to Mainz, Hauptbahnhofbus bus
    3. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    4. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    8h 39m
    €121–531

  10. Fly to Il Caravaggio International Airport, bus, train

    1. Fly from Palermo Airport (PMO) to Il Caravaggio International Airport (BGY)plane plane PMO - BGY
    2. Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus bus
    3. Take the train from Milano Centrale to Karlsruhe Hbftrain train
    11h 39m
    €147–438

  11. Bus via Milan

    1. Take the bus from Palermo to Milano, Autostazione Lampugnanobus bus N597
    2. Take the bus from Milano, Autostazione Lampugnano to Karlsruhe central train stationbus bus N77
    33h 5m
    €192–289

Palermo to Karlsruhe by train

Calendar7Weekly Trains
Duration21h 54mAverage Duration
Ticket€270Cheapest Price
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Comparing Your Travel Options

Map of how to get from Palermo to Karlsruhe.ExpandLaunch map view
  • Distance: 1,530.1 km
  • Duration: 7h 12m

What companies run services between Palermo, Italy and Karlsruhe, Germany?

You can take a train from Palermo Centrale to Karlsruhe Hbf via Roma Termini and Milano Centrale in around 21h 54m. Alternatively, Onebus operates a bus from Palermo Piazza Cairoli to Karlsruhe Central Bus Station once a week. Tickets cost €260–370 and the journey takes 32h 59m.

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