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How to get fromPalermo to Madridby plane, train (Trenitalia, Renfe, Ouigo), ferry, car ferry, train, or bus

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There are 7 ways to get from Palermo to Madrid by plane, train (Trenitalia, Renfe, Ouigo), ferry, car ferry, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Palermo Airport

    best
    1. Fly from Palermo Airport (PMO) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PMO - MAD
    5h 49m
    €55–227

  2. Train

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Milano Centraletrain train
    3. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    5. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    29h 24m
    €334–633

  3. Ferry, car ferry, train

    1. Take the ferry from Palermo to Civitavecchiaferry ferry
    2. Take the carferry from Port of Civitavecchia to Port de Barcelonacarferry car ferry
    3. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    37h 52m
    €200–390

  4. Bus

    1. Take the bus from Palermo to Milano, Autostazione Lampugnanobus bus N597
    2. Take the bus from Milan to Madridbus bus FlixBus N1138
    46h 25m
    €281–426

  5. Bus to Trapani Airport, fly

    1. Take the bus from Palermo Via Belgio/Via dei Nebrodi to Trapani Birgi Airportbus bus
    2. Fly from Trapani Airport (TPS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane TPS - MAD
    8h 40m
    €108–491

  6. Bus to Catania–Fontanarossa Airport, fly

    1. Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane CTA - MAD
    7h 55m
    €63–239

  7. Bus, train

    1. Take the bus from Palermo Piazza Cairoli to Verona Porta Nuova Stationbus bus
    2. Take the train from Verona Porta Nuova to Padovatrain train Fr
    3. Take the bus from Padova to Méndez Álvaro Estación Surbus bus
    2d 5h
    €338–461

Palermo to Madrid by train

Calendar7Weekly Trains
Duration29h 24mAverage Duration
Ticket€334Cheapest Price
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Comparing Your Travel Options

Map of how to get from Palermo to Madrid.ExpandLaunch map view
  • Distance: 1,497.2 km
  • Duration: 5h 49m

What companies run services between Palermo, Italy and Madrid, Spain?

Ryanair, Iberia, and Vueling Airlines fly from Palermo Airport (PMO) to Adolfo Suárez Madrid–Barajas Airport (MAD) 3 times a day. Alternatively, you can take a train from Palermo Centrale to Madrid-Puerta de Atocha-Almudena Grandes via Roma Termini, Milano Centrale, Lyon Part Dieu, and Barcelona-Sants in around 29h 24m.

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