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How to get fromPalermo to Mainzby plane, train, ferry, car ferry, car, or bus

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There are 10 ways to get from Palermo to Mainz by plane, train, ferry, car ferry, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Palermo Airport to Frankfurt

    best
    1. Fly from Palermo Airport (PMO) to Frankfurt (FRA)plane plane PMO - FRA
    5h 47m
    €75–219

  2. Train, ferry

    1. Take the train from Palermo Centrale to Messina Centraletrain train Re
    2. Take the ferry from Messina Marittima to Villa S.Giovanniferry ferry M1 / ...
    3. Take the train from Villa S.Giovanni to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train 55 / ...
    21h 59m

  3. Car ferry, drive

    1. Take the carferry from Port of Palermo to Port of Genoacarferry car ferry
    2. Drive from Port of Genoa to Mainzcar car
    28h 16m
    €224–331

  4. Bus

    1. Take the bus from Palermo Piazza Cairoli to Mühlheim am Mainbus bus
    31h 15m
    €258–349

  5. Bus to Catania–Fontanarossa Airport, fly to Frankfurt

    1. Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Frankfurt (FRA)plane plane CTA - FRA
    7h 38m
    €93–238

  6. Fly Palermo Airport to Stuttgart Airport, train

    1. Fly from Palermo Airport (PMO) to Stuttgart Airport (STR)plane plane PMO - STR
    2. Take the train from Hauptbahnhof to Frankfurttrain train
    7h 44m
    €109–396

  7. Fly Palermo Airport to Hahn, bus

    1. Fly from Palermo Airport (PMO) to Hahn (HHN)plane plane PMO - HHN
    2. Take the bus from Hahn to Mainz, Hauptbahnhofbus bus
    7h 15m
    €78–292

  8. Fly Palermo Airport to Cologne Bonn Airport, train

    1. Fly from Palermo Airport (PMO) to Cologne Bonn Airport (CGN)plane plane PMO - CGN
    2. Take the train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbftrain train
    7h 14m
    €93–451

  9. Bus via Milan

    1. Take the bus from Palermo to Milano, Autostazione Lampugnanobus bus N597
    2. Take the bus from Milan to Mainz central train stationbus bus FlixBus 476
    35h 35m
    €175–281

  10. Bus #2

    1. Take the bus from Palermo Piazza Cairoli to Wiesbaden Gartenfeldstraße P+Rbus bus
    37h 27m
    €294–399

Palermo Airport (PMO) to Frankfurt (FRA) flights

Calendar36Weekly Planes
Duration4h 22mAverage Duration
Ticket€90Cheapest Price
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Questions & Answers

Map of how to get from Palermo to Mainz.ExpandLaunch map view
  • Distance: 1,424.6 km
  • Duration: 5h 47m

What companies run services between Palermo, Italy and Mainz, Germany?

Lufthansa, ITA Airways, and Air Dolomiti fly from Palermo Airport (PMO) to Frankfurt (FRA) 5 times a day. Alternatively, Onebus operates a bus from Palermo Piazza Cairoli to Mühlheim am Main once a week. Tickets cost €250–350 and the journey takes 28h 18m.

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