There are 6 ways to get from Palermo to Mesagne by plane, bus, train (Trenitalia), car, car ferry, train, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Palermo Airport (PMO) to Brindisi Airport (BDS)plane PMO - BDS
- Take the bus from Brindisi Via N.Brandi to Mesagnebus
4h 32m€56–138Bus via Messina
cheapest- Take the bus from Palermo Oreto Orsi to Messina Piazza della Repubblicabus Sais Autolinee 8902 / ...
- Take the bus from Messina - Piazza della Repubblica to Brindisibus
13h 2m€44–66Train (Trenitalia)
- Take the train from Palermo Centrale to Lamezia Terme C.train Ic
- Take the train from Lamezia Terme C. to Tarantotrain Ic
- Take the train from Taranto to Mesagnetrain Re
11h 23m€69–137Drive, car ferry
- Drive from Palermo to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Mesagnecar
7h 53m€122–189Train, ferry (Trenitalia)
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Francavilla Fontanatrain Ic
11h 30mBus
- Take the bus from Palermo to Sibaribus 582
- Take the bus from Sibari to Brindisibus
15h 41m€64–111
Palermo to Mesagne by train (Trenitalia)
Questions & Answers
The cheapest way to get from Palermo to Mesagne is to bus via Messina which costs €40 - €70 and takes 13h 2m.
The fastest way to get from Palermo to Mesagne is to fly and bus which takes 4h 32m and costs €55 - €140.
No, there is no direct bus from Palermo to Mesagne. However, there are services departing from Galilei Giotto and arriving at Mesagne via Palermo Oreto Orsi, Messina - Piazza della Repubblica and Brindisi Viale A.Moro. The journey, including transfers, takes approximately 13h 2m.
No, there is no direct train from Palermo to Mesagne. However, there are services departing from Palermo Centrale and arriving at Mesagne via Lamezia Terme C. and Taranto. The journey, including transfers, takes approximately 11h 23m.
The distance between Palermo and Mesagne is 551 km.
The best way to get from Palermo to Mesagne without a car is to train which takes 11h 23m and costs €65 - €140.
It takes approximately 4h 32m to get from Palermo to Mesagne, including transfers.
Palermo to Mesagne bus services, operated by FlixBus, depart from Palermo station.
Palermo to Mesagne train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo to Mesagne is to train which takes 11h 23m and costs €65 - €140. Alternatively, you can bus via Messina, which costs €40 - €70 and takes 13h 2m.
What companies run services between Palermo, Italy and Mesagne, Italy?
You can take a train from Palermo Centrale to Mesagne via Lamezia Terme C. and Taranto in around 11h 23m. Alternatively, you can take a bus from Galilei Giotto to Mesagne via Palermo Oreto Orsi, Messina Piazza della Repubblica, Messina - Piazza della Repubblica, Brindisi, and Brindisi Viale A.Moro in around 13h 2m.
- Website
- ryanair.com
Flights from Palermo Airport to Brindisi Airport
- Ave. Duration
- 1h 15m
- When
- Tuesday and Saturday
- Estimated price
- €45–140
Flights from Palermo Airport to Brindisi Airport via Rome
- Ave. Duration
- 3h 30m
- When
- Wednesday
- Estimated price
- €45–140
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Lamezia Terme C.
- Ave. Duration
- 5h 44m
- Frequency
- Twice daily
- Estimated price
- €35–75
- Website
- Trenitalia Intercity
Train from Lamezia Terme C. to Taranto
- Ave. Duration
- 2h 49m
- Frequency
- Twice daily
- Estimated price
- €27–55
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- €24–50
- Website
- Trenitalia Intercity
Train from Villa S.Giovanni to Francavilla Fontana
- Ave. Duration
- 5h 5m
- Frequency
- Once a week
- Estimated price
- €40–85
- Website
- Trenitalia Intercity
- Phone
- 800232042, 3667880781
- Website
- stpbrindisi.it
Bus from Brindisi Via N.Brandi to Mesagne
- Ave. Duration
- 27 min
- Frequency
- Hourly
- Estimated price
- €1
- Schedules at
- stpbrindisi.it
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Tresmestieri to Villa S. Giovanni
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
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More Questions & Answers
Palermo to Mesagne bus services, operated by FlixBus, arrive at Sibari station.
Palermo to Mesagne train services, operated by Trenitalia Intercity, arrive at Lamezia Terme C. station.
Book your Palermo to Mesagne train tickets online with Omio.
Book your Palermo to Mesagne bus tickets online with Omio.
There are 1764+ hotels available in Mesagne.














