There are 6 ways to get from Palermo to Mesagne by plane, bus, train, ferry, night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Palermo Airport (PMO) to Brindisi Airport (BDS)plane PMO - BDS
- Take the bus from Brindisi Via N.Brandi to Mesagnebus
4h 32m€61–147Bus via Messina
cheapest- Take the bus from Palermo Oreto Orsi to Messina Piazza della Repubblicabus Sais Autolinee 8902 / ...
- Take the bus from Messina - Piazza della Repubblica to Brindisibus
13h 2m€44–66Train, ferry (Trenitalia)
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Amanteatrain Re
- Take the train from Amantea to Tarantotrain Ic
- Take the train from Taranto to Mesagnetrain Re
10h 52mNight train, train
- Take the nighttrain from Palermo Centrale to Lamezia Terme C.nighttrain Ini
- Take the train from Lamezia Terme C. to Francavilla Fontanatrain Ic
13h 13m€63–110Bus
- Take the bus from Palermo to Sibaribus 582
- Take the bus from Sibari to Brindisibus
15h 41m€65–101Drive, car ferry
- Drive from Palermo to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Mesagnecar
7h 53m€122–190
Palermo Airport (PMO) to Brindisi Airport (BDS) flights
Comparing Your Travel Options
The cheapest way to get from Palermo to Mesagne is to bus via Messina which costs €40 - €70 and takes 13h 2m.
The fastest way to get from Palermo to Mesagne is to fly and bus which takes 4h 32m and costs €60 - €150.
No, there is no direct bus from Palermo to Mesagne. However, there are services departing from Galilei Giotto and arriving at Mesagne via Palermo Oreto Orsi, Messina - Piazza della Repubblica and Brindisi Viale A.Moro. The journey, including transfers, takes approximately 13h 2m.
No, there is no direct train from Palermo to Mesagne. However, there are services departing from Palermo Notarbartolo and arriving at Mesagne via Palermo Centrale, Lamezia Terme C. and Francavilla Fontana. The journey, including transfers, takes approximately 13h 13m.
The distance between Palermo and Mesagne is 551 km.
The best way to get from Palermo to Mesagne without a car is to train and ferry which takes 10h 52m and costs .
It takes approximately 4h 32m to get from Palermo to Mesagne, including transfers.
Palermo to Mesagne bus services, operated by FlixBus, depart from Palermo station.
Palermo to Mesagne train services, operated by Trenitalia Intercity Night, depart from Palermo Centrale station.
Palermo to Mesagne bus services, operated by FlixBus, arrive at Sibari station.
What companies run services between Palermo, Italy and Mesagne, Italy?
You can take a bus from Galilei Giotto to Mesagne via Palermo Oreto Orsi, Messina Piazza della Repubblica, Messina - Piazza della Repubblica, Brindisi, and Brindisi Viale A.Moro in around 13h 2m.
- Website
- ita-airways.com
Flights from Palermo Airport to Brindisi Airport via Rome
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- €95–140
- Website
- ryanair.com
Flights from Palermo Airport to Brindisi Airport
- Ave. Duration
- 1h 15m
- When
- Wednesday
- Estimated price
- €45–160
Flights from Palermo Airport to Brindisi Airport via Rome
- Ave. Duration
- 3h 30m
- When
- Wednesday
- Estimated price
- €45–160
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Villa S.Giovanni to Amantea
- Ave. Duration
- 1h 33m
- Frequency
- Hourly
- Estimated price
- €16–23
- Website
- Trenitalia
Train from Taranto to Mesagne
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- €6–9
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
Train from Villa S.Giovanni to Amantea
- Ave. Duration
- 1h 23m
- Frequency
- Every 4 hours
- Estimated price
- €14–27
- Website
- Trenitalia Intercity
Train from Amantea to Taranto
- Ave. Duration
- 2h 29m
- Frequency
- 4 times a day
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
Train from Lamezia Terme C. to Francavilla Fontana
- Ave. Duration
- 3h 27m
- Frequency
- Twice daily
- Estimated price
- €30–55
- Website
- Trenitalia Intercity
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Palermo Centrale to Lamezia Terme C.
- Ave. Duration
- 6h 17m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- Trenitalia ICN
- Phone
- 800232042, 3667880781
- Website
- stpbrindisi.it
Bus from Brindisi Via N.Brandi to Mesagne
- Ave. Duration
- 27 min
- Frequency
- Hourly
- Estimated price
- €1
- Schedules at
- stpbrindisi.it
- Phone
- 800 21 10 20
- [email protected]
- Website
- SAIS Autolinee
Bus from Palermo Oreto Orsi to Messina Piazza della Repubblica
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- €12–18
- Schedules at
- SAIS Autolinee
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Messina - Piazza della Repubblica to Brindisi
- Ave. Duration
- 6h 35m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Website
- SAIS Transporti
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Palermo to Sibari
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- €45–75
- Website
- Flixbus
- Phone
- +390981 500331
- [email protected]
- Website
- saj.it
Bus from Sibari to Brindisi
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a week
- Estimated price
- €16–28
- Schedules at
- saj.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Tresmestieri to Villa S. Giovanni
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
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Booking & Getting There
Palermo to Mesagne train services, operated by Trenitalia Intercity Night, arrive at Lamezia Terme C. station.
Book your Palermo to Mesagne bus tickets online with Omio.
There are 1612+ hotels available in Mesagne.



































