There are 8 ways to get from Palermo to Prague by plane, train, ferry, bus, car, train (Trenitalia), or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Palermo Airport
best- Fly from Palermo Airport (PMO) to Václav Havel Airport Prague (PRG)plane PMO - PRG
5h 30mKč 1,748–5,703Bus to Catania–Fontanarossa Airport, fly
cheapest- Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus
- Fly from Catania–Fontanarossa Airport (CTA) to Václav Havel Airport Prague (PRG)plane CTA - PRG
7h 26mKč 1,740–4,898Train, ferry
- Take the train from Palermo Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Venezia Mestretrain Fr
- Take the train from Venezia Mestre to Wien Hbftrain Rjx / ...
- Take the train from Wien Hbf to Praha Hlavni Nadrazitrain Rj / ...
26h 33mBus
- Take the bus from Palermo Piazza Cairoli to München Hackerbrückebus
- Take the bus from Munich central bus station to Praguebus FlixBus 183 / ...
33h 16mKč 6,128–8,715Ferry, drive
- Take the ferry from Port of Palermo to Naples Beverelloferry
- Drive from Naples Beverello to Praguecar
23h 3mKč 6,302–10,147Train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Bolzano Bozentrain Fr
- Take the train from Bolzano Bozen to Innsbruck Hauptbahnhoftrain Re
- Take the train from Innsbruck Hauptbahnhof to Linz/Donau Hbftrain Rjx
- Take the train from Linz/Donau Hbf to Praha Hlavni Nadrazitrain Ec
28h 46mKč 6,940–13,358Bus via Rome
- Take the bus from Palermo Terminal Bus to Roma, Autostazione Tiburtinabus Autoservizi Salemi S202
- Take the bus from Rome Tiburtina Bus Station to Prague Florenc Central Bus Stationbus : Prague Central Bus Station - Rome Tiburtina Bus Station / ...
33h 25mKč 3,020–4,592Train, night train
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the nighttrain from Roma Tiburtina to Linz/Donau Hbfnighttrain En
- Take the train from Linz/Donau Hbf to Praha Hlavni Nadrazitrain Ec
33h 42mKč 8,131–13,351
Palermo Airport (PMO) to Václav Havel Airport Prague (PRG) flights
Comparing Your Travel Options
The cheapest way to get from Palermo to Prague is to bus and fly which costs 1 700 Kč - 4 900 Kč and takes 7h 26m.
The fastest way to get from Palermo to Prague is to fly which takes 5h 30m and costs 1 700 Kč - 6 000 Kč.
No, there is no direct bus from Palermo to Prague. However, there are services departing from Palermo Piazza Cairoli and arriving at Prague via Munich central bus station. The journey, including transfers, takes approximately 33h 16m.
No, there is no direct train from Palermo to Prague. However, there are services departing from Palermo Centrale and arriving at Praha Hlavni Nadrazi via Roma Termini, Bolzano Bozen, Innsbruck Hauptbahnhof and Linz/Donau Hbf. The journey, including transfers, takes approximately 28h 46m.
The distance between Palermo and Prague is 1375 km.
The best way to get from Palermo to Prague without a car is to train and ferry which takes 26h 33m and costs .
It takes approximately 5h 30m to get from Palermo to Prague, including transfers.
Palermo to Prague bus services, operated by Onebus, depart from Palermo Piazza Cairoli station.
Palermo to Prague train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo to Prague is to fly which takes 5h 30m and costs 1 700 Kč - 6 000 Kč. Alternatively, you can bus, which costs 6 000 Kč - 9 000 Kč and takes 33h 16m, you could also train, which costs 6 500 Kč - 14 000 Kč and takes 28h 46m.
What companies run services between Palermo, Italy and Prague, Czechia?
Ulendo Airlink, Ryanair, and two other airlines fly from Palermo Airport (PMO) to Václav Havel Airport Prague (PRG) twice daily. Alternatively, you can take a bus from Palermo Piazza Cairoli to Prague via München Hackerbrücke and Munich central bus station in around 33h 16m.
- Website
- ryanair.com
Flights from Palermo Airport to Václav Havel Airport Prague
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- Kč 1,700–4,800
Flights from Catania–Fontanarossa Airport to Václav Havel Airport Prague
- Ave. Duration
- 2h 25m
- When
- Monday and Friday
- Estimated price
- Kč 1,400–3,400
Flights from Catania–Fontanarossa Airport to Václav Havel Airport Prague via Pescara
- Ave. Duration
- 4h 40m
- When
- Friday and Sunday
- Estimated price
- Kč 1,400–3,400
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- Kč 600–900
- Website
- Trenitalia
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to München Hackerbrücke
- Ave. Duration
- 27h 6m
- Frequency
- Once a week
- Estimated price
- Kč 5,500–8,000
- Website
- Onebus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Czechia
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Travelling by boat in Italy
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Palermo to Prague bus services, operated by Onebus, arrive at München Hackerbrücke station.
Palermo to Prague train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Palermo to Prague train tickets online with Omio.
Book your Palermo to Prague bus tickets online with Omio.
There are 4560+ hotels available in Prague.


