There are 8 ways to get from Palermo to Santander by plane, car ferry, car, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Santander Airport
best- Fly from Palermo Airport (PMO) to Santander Airport (SDR)plane PMO - SDR
7h 4m€74–356Fly to Bilbao Airport, bus
cheapest- Fly from Palermo Airport (PMO) to Bilbao Airport (BIO)plane PMO - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 4m€73–272Car ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Santandercar
33h 9m€306–451Train, bus
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Genova P.Za Principetrain Fa / ...
- Take the bus from Genoa to Marseillebus
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
39h 3m€371–699Bus
- Take the bus from Palermo to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Bordeauxbus
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
42h 35m€221–368Car ferry, bus, train
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Take the bus from Genoa to Toulonbus
- Take the train from Toulon to Marseille St Charlestrain Ter
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
42h 17m€337–539Ferry, car ferry, train
- Take the ferry from Palermo to Civitavecchiaferry
- Take the carferry from Port of Civitavecchia to Port de Barcelonacarferry
- Take the train from Barcelona-Sants to Bilbao-Abandotrain Alv
- Take the train from Bilbao to Santandertrain
47h 9m€253–407Bus, train
- Take the bus from Palermo Piazza Cairoli to Verona Porta Nuova Stationbus
- Take the train from Verona Porta Nuova to Padovatrain Fr
- Take the bus from Padova to Estación de autobuses de Santanderbus
2d 2h€338–501
Palermo to Santander by train and bus
Questions & Answers
The cheapest way to get from Palermo to Santander is to fly and bus which costs €70 - €280 and takes 8h 4m.
The fastest way to get from Palermo to Santander is to fly which takes 7h 4m and costs €70 - €360.
No, there is no direct bus from Palermo to Santander. However, there are services departing from Palermo and arriving at Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux. The journey, including transfers, takes approximately 42h 35m.
The distance between Palermo and Santander is 1567 km.
The best way to get from Palermo to Santander without a car is to train and bus which takes 39h 3m and costs €370 - €700.
It takes approximately 7h 4m to get from Palermo to Santander, including transfers.
Palermo to Santander bus services, operated by FlixBus, depart from Palermo station.
The best way to get from Palermo to Santander is to fly which takes 7h 4m and costs €70 - €360. Alternatively, you can bus, which costs €220 - €370 and takes 42h 35m.
Palermo to Santander bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Book your Palermo to Santander bus tickets online with Omio and FlixBus.
What companies run services between Palermo, Italy and Santander, Spain?
Vueling Airlines, Ryanair, and Ulendo Airlink fly from Palermo Airport (PMO) to Santander Airport (SDR) once daily. Alternatively, you can take a bus from Palermo to Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux in around 42h 35m.
- Website
- vueling.com
Flights from Palermo Airport to Santander Airport via Barcelona
- Ave. Duration
- 5h 2m
- When
- Sunday and Monday
- Estimated price
- €80–340
Flights from Palermo Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- €75–240
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 29m
- Frequency
- 4 times a day
- Estimated price
- €95–200
- Website
- Trenitalia Intercity
Train from Roma Termini to Genova P.Za Principe
- Ave. Duration
- 6h 41m
- Frequency
- 5 times a day
- Estimated price
- €50–110
- Website
- Trenitalia Intercity
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Genoa to Marseille
- Ave. Duration
- 6h 35m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Palermo to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 20m
- Frequency
- Twice daily
- Estimated price
- €95–160
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Bordeaux
- Ave. Duration
- 17h 10m
- Frequency
- Once daily
- Estimated price
- €95–160
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- Flixbus
Bus from Genoa to Toulon
- Ave. Duration
- 4h 40m
- Frequency
- 3 times a day
- Estimated price
- €25–45
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Ferry from Palermo to Civitavecchia
- Ave. Duration
- 13h 45m
- Frequency
- 3 times a week
- Estimated price
- €45–90
- Website
- Grandi Navi Veloci
Car ferry from Port of Civitavecchia to Port de Barcelona
- Ave. Duration
- 19h 30m
- Frequency
- Once a week
- Estimated price
- €110–160
- Website
- Grandi Navi Veloci
Want to know more about travelling around Spain
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