There are 8 ways to get from Palermo to Santander by plane, car ferry, car, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Santander Airport
best- Fly from Palermo Airport (PMO) to Santander Airport (SDR)plane PMO - SDR
7h 44m€99–385Fly to Asturias Airport, bus
cheapest- Fly from Palermo Airport (PMO) to Asturias Airport (OVD)plane PMO - OVD
- Take the bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]bus
- Take the bus from Oviedo to Estación de autobuses de Santanderbus
12h 6m€84–327Car ferry, drive
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Santandercar
33h 9m€303–444Train, bus
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Toulouse Matabiautrain Tgv
- Take the bus from Toulouse to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
34h 26m€362–607Bus
- Take the bus from Palermo to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Bordeauxbus
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
42h 35m€258–396Fly to Bilbao Airport, bus
- Fly from Palermo Airport (PMO) to Bilbao Airport (BIO)plane PMO - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 23m€93–442Ferry, car ferry, bus
- Take the ferry from Palermo to Civitavecchiaferry
- Take the carferry from Port of Civitavecchia to Port de Barcelonacarferry
- Take the bus from Barcelona, Estació d'Autobusos Nord to Estación de autobuses de Santanderbus
45h 49m€204–324Bus, train
- Take the bus from Palermo Piazza Cairoli to Verona Porta Nuova Stationbus
- Take the train from Verona Porta Nuova to Padovatrain Fr
- Take the bus from Padova to Estación de autobuses de Santanderbus
2d 2h€338–451
Palermo to Santander by train and bus
Comparing Your Travel Options
The cheapest way to get from Palermo to Santander is to fly and bus which costs €80 - €330 and takes 12h 6m.
The fastest way to get from Palermo to Santander is to fly which takes 7h 44m and costs €95 - €390.
No, there is no direct bus from Palermo to Santander. However, there are services departing from Palermo and arriving at Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux. The journey, including transfers, takes approximately 42h 35m.
The distance between Palermo and Santander is 1567 km.
The best way to get from Palermo to Santander without a car is to train and bus which takes 34h 26m and costs €360 - €650.
It takes approximately 7h 44m to get from Palermo to Santander, including transfers.
Palermo to Santander bus services, operated by FlixBus, depart from Palermo station.
The best way to get from Palermo to Santander is to fly which takes 7h 44m and costs €95 - €390. Alternatively, you can bus, which costs €250 - €400 and takes 42h 35m.
Palermo to Santander bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Book your Palermo to Santander bus tickets online with Omio and FlixBus.
What companies run services between Palermo, Italy and Santander, Spain?
Ryanair, Volotea, and two other airlines fly from Palermo Airport (PMO) to Santander Airport (SDR) 6 times a week. Alternatively, you can take a bus from Palermo to Estación de autobuses de Santander via Florence Villa Constanza Bus Station and Bordeaux in around 42h 35m.
- Website
- iberia.com
Flights from Palermo Airport to Santander Airport via Madrid
- Ave. Duration
- 7h 2m
- When
- Saturday and Sunday
- Estimated price
- €95–380
Flights from Palermo Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 26m
- When
- Wednesday, Thursday, Saturday, Monday, Sunday, and Friday
- Estimated price
- €55–260
Flights from Palermo Airport to Asturias Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €75–310
Flights from Palermo Airport to Asturias Airport via Madrid
- Ave. Duration
- 6h 45m
- When
- Saturday
- Estimated price
- €75–300
- Website
- vueling.com
Flights from Palermo Airport to Santander Airport via Madrid
- Ave. Duration
- 7h 2m
- When
- Saturday and Sunday
- Estimated price
- €95–380
Flights from Palermo Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 26m
- When
- Wednesday, Thursday, Saturday, Monday, Sunday, and Friday
- Estimated price
- €55–260
Flights from Palermo Airport to Asturias Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €75–310
Flights from Palermo Airport to Asturias Airport via Madrid
- Ave. Duration
- 6h 45m
- When
- Saturday
- Estimated price
- €75–300
- Website
- volotea.com
Flights from Palermo Airport to Santander Airport via Valencia
- Ave. Duration
- 5h 20m
- When
- Friday
- Estimated price
- €95–380
Flights from Palermo Airport to Bilbao Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday
- Estimated price
- €60–290
Flights from Palermo Airport to Asturias Airport via Barcelona
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €75–300
Flights from Palermo Airport to Asturias Airport via Rome
- Ave. Duration
- 5h 25m
- When
- Saturday
- Estimated price
- €85–350
- Website
- ryanair.com
Flights from Palermo Airport to Santander Airport via Bologna
- Ave. Duration
- 6h 41m
- When
- Sunday
- Estimated price
- €100–390
- Website
- ita-airways.com
Flights from Palermo Airport to Asturias Airport via Rome
- Ave. Duration
- 6h
- When
- Monday and Saturday
- Estimated price
- €85–350
Flights from Palermo Airport to Asturias Airport via Barcelona
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €75–300
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 19m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
Train from Verona Porta Nuova to Padova
- Ave. Duration
- 43 min
- Frequency
- Hourly
- Estimated price
- €9–16
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 43m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Verona Porta Nuova to Padova
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €9–14
- Website
- Trenitalia
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Toulouse Matabiau
- Ave. Duration
- 4h 12m
- Frequency
- 3 times a day
- Estimated price
- €110–170
- Website
- TGV inOui
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Verona Porta Nuova to Padova
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia Frecce
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Toulouse to Bilbao Intermodal
- Ave. Duration
- 5h 30m
- Frequency
- 5 times a week
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Palermo to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 20m
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Bordeaux
- Ave. Duration
- 17h 10m
- Frequency
- 5 times a week
- Estimated price
- €110–170
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
Bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Website
- ALSA
Bus from Oviedo to Estación de autobuses de Santander
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- €17–26
- Website
- ALSA
Bus from Barcelona, Estació d'Autobusos Nord to Estación de autobuses de Santander
- Ave. Duration
- 9h 30m
- Frequency
- 3 times a day
- Estimated price
- €55–90
- Website
- ALSA
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Palermo Piazza Cairoli to Verona Porta Nuova Station
- Ave. Duration
- 23h 51m
- Frequency
- Once a week
- Estimated price
- €200–290
- Website
- Onebus
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Padova to Estación de autobuses de Santander
- Ave. Duration
- 24h 34m
- Frequency
- 3 times a week
- Estimated price
- €120–150
- Schedules at
- tabitatour.ro
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Palermo to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Ferry from Palermo to Civitavecchia
- Ave. Duration
- 13h 45m
- Frequency
- 3 times a week
- Estimated price
- €45–85
- Website
- Grandi Navi Veloci
Car ferry from Port of Civitavecchia to Port de Barcelona
- Ave. Duration
- 19h 30m
- Frequency
- Once a week
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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