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How to get fromPalermo to Sienaby plane, train, train (Trenitalia), ferry, car, or bus

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There are 9 ways to get from Palermo to Siena by plane, train, train (Trenitalia), ferry, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Palermo Airport to Florence Peretola Airport, train

    best
    1. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane plane PMO - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    5h 27m
    €72–207

  2. Fly Palermo Airport to Bologna Guglielmo Marconi Airport, train

    cheapest
    1. Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane PMO - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 1m
    €40–212

  3. Train (Trenitalia)

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    15h 3m
    €131–290

  4. Ferry, drive

    1. Take the ferry from Palermo to Civitavecchiaferry ferry
    2. Drive from Civitavecchia to Sienacar car
    16h 9m
    €77–134

  5. Bus

    1. Take the bus from Palermo to Sienabus bus N597
    16h 20m
    €95–160

  6. Fly Palermo Airport to Pisa International Airport, train

    1. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    5h 19m
    €56–246

  7. Bus to Trapani Airport, fly to Pisa International Airport, train

    1. Take the bus from Palermo Via Belgio/Via dei Nebrodi to Trapani Birgi Airportbus bus
    2. Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)plane plane TPS - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    6h
    €59–319

  8. Train via Chiusi (Trenitalia)

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Chiusi-Chianciano T.train train
    3. Take the train from Chiusi-Chianciano T. to Sienatrain train Re
    17h
    €118–254

  9. Bus via Florence

    1. Take the bus from Palermo Piazza Cairoli to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    21h 43m

Palermo to Siena by train (Trenitalia)

Calendar28Weekly Trains
Duration15h 3mAverage Duration
Ticket€131Cheapest Price
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Questions & Answers

Map of how to get from Palermo to Siena.ExpandLaunch map view
  • Distance: 773.5 km
  • Duration: 5h 27m

What companies run services between Palermo, Italy and Siena, Italy?

You can take a train from Palermo Centrale to Siena via Roma Termini and Firenze S.M.N. in around 15h 3m. Alternatively, FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €95–160 and the journey takes 16h 20m.

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