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How to get fromPalermo to Sienaby plane, train, ferry, car, or bus

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There are 8 ways to get from Palermo to Siena by plane, train, ferry, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Palermo Airport to Florence Peretola Airport, train

    best
    1. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane plane PMO - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    5h 36m
    €77–197

  2. Fly Palermo Airport to Bologna Guglielmo Marconi Airport, train

    cheapest
    1. Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane PMO - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 1m
    €47–212

  3. Ferry, drive

    1. Take the ferry from Palermo to Civitavecchiaferry ferry
    2. Drive from Civitavecchia to Sienacar car
    16h 9m
    €77–128

  4. Bus

    1. Take the bus from Palermo to Sienabus bus N597
    16h 20m
    €100–170

  5. Fly Palermo Airport to Pisa International Airport, train

    1. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    5h 19m
    €49–216

  6. Bus to Trapani Airport, fly to Pisa International Airport, train

    1. Take the bus from Palermo Via Belgio/Via dei Nebrodi to Trapani Birgi Airportbus bus
    2. Fly from Trapani Airport (TPS) to Pisa International Airport (PSA)plane plane TPS - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    6h
    €59–169

  7. Ferry, train

    1. Take the ferry from Palermo to Civitavecchiaferry ferry
    2. Take the train from Civitavecchia to Grossetotrain train Fb / ...
    3. Take the train from Grosseto to Sienatrain train Re
    19h 1m
    €73–140

  8. Bus via Florence

    1. Take the bus from Palermo Piazza Cairoli to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    21h 50m

Palermo to Siena by bus

Calendar7Weekly Buses
Duration16h 20mAverage Duration
Ticket€100Cheapest Price
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Questions & Answers

Map of how to get from Palermo to Siena.ExpandLaunch map view
  • Distance: 773.5 km
  • Duration: 5h 36m

What companies run services between Palermo, Italy and Siena, Italy?

FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €100–170 and the journey takes 16h 20m.

Airlines
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Bus operators
Ferry operators

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