There are 8 ways to get from Palm Bay to Knoxville by car, plane, train, bus, bus (Greyhound, Flixbus), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Orlando Sanford, fly to Mcghee Tyson Airport
best- Drive from Palm Bay to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane SFB - TYS
3h 30m$179–740Drive to Orlando Sanford, fly to Asheville Regional Airport, drive
cheapest- Drive from Palm Bay to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
5h 22m$91–395Drive, train, bus
- Drive from Palm Bay to Kissimmee Amtrak Stationcar
- Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York, NY to Knoxville, TNbus Ny
37h 37m$518–928Bus
- Take the bus from Sebastian to Jacksonvillebus
- Take the bus from Jacksonville to New York City Chinatownbus
- Take the bus from New York, NY to Knoxville, TNbus Ny
41h 41m$368–549Drive 700.5 mi
- Drive from Palm Bay to Knoxvillecar 700.5 mi
11h 53m$128–185Fly Melbourne International Airport to Mcghee Tyson Airport
- Fly from Melbourne International Airport (MLB) to Mcghee Tyson Airport (TYS)plane MLB - TYS
5h 51m$176–722Shuttle to Orlando, fly to Mcghee Tyson Airport
- Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airport
- Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane MCO - TYS
6h 49m$214–738Bus, train
- Take the bus from Sebastian to West Palm Beach Bus Stationbus
- Take the train from West Palm Beach Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York to Knoxvillebus Nyc
43h 56m$706–1,275
Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Palm Bay to Knoxville is to drive which costs $120 - $190 and takes 11h 53m.
The fastest way to get from Palm Bay to Knoxville is to drive and fly which takes 3h 30m and costs $170 - $750.
No, there is no direct bus from Palm Bay to Knoxville station. However, there are services departing from Sebastian and arriving at Knoxville Station Hall of Fame via Jacksonville, New York, NY, Walmart and Charlie Haun WB Aft Washington PK. The journey, including transfers, takes approximately 41h 41m.
The distance between Palm Bay and Knoxville is 605 miles. The road distance is 704.6 miles.
The best way to get from Palm Bay to Knoxville without a car is to bus which takes 41h 41m and costs $360 - $550.
It takes approximately 3h 30m to get from Palm Bay to Knoxville, including transfers.
Palm Bay to Knoxville bus services, operated by Greyhound USA, depart from Sebastian station.
The best way to get from Palm Bay to Knoxville is to bus which takes 41h 41m and costs $360 - $550. Alternatively, you can fly, which costs $170 - $750 and takes 5h 51m.
Palm Bay to Knoxville bus services, operated by Greyhound USA, arrive at Jacksonville station.
Yes, the driving distance between Palm Bay to Knoxville is 705 miles. It takes approximately 11h 53m to drive from Palm Bay to Knoxville.
What companies run services between Palm Bay, Brevard County, FL, USA and Knoxville, TN, USA?
You can take a vehicle from Palm Bay to Knoxville Station Hall of Fame via Sebastian, Jacksonville, New York, NY, Knoxville, TN, Walmart, and Charlie Haun WB Aft Washington PK in around 41h 41m. Alternatively, Delta and American Airlines fly from Melbourne International Airport (MLB) to Mcghee Tyson Airport (TYS) 4 times a day.
- Website
- allegiantair.com
Flights from Orlando Sanford to Mcghee Tyson Airport
- Ave. Duration
- 1h 38m
- When
- Thursday, Sunday, Friday, Wednesday, Monday, and Saturday
- Estimated price
- $110–650
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $55–340
Flights from Orlando to Mcghee Tyson Airport
- Ave. Duration
- 1h 44m
- When
- Friday and Monday
- Estimated price
- $100–600
- Website
- delta.com
Flights from Melbourne International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $120–650
Flights from Orlando to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Melbourne International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $130–700
Flights from Orlando to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Orlando to Mcghee Tyson Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 22h 53m
- Frequency
- Once daily
- Estimated price
- $370–750
- Website
- https://www.amtrak.com/home.html
Train from West Palm Beach Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 26h 8m
- Frequency
- Once daily
- Estimated price
- $430–900
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 615-939-8887
- [email protected]
- Website
- nytnbus.com
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- https://www.nytnbus.com
- Adult One-way
- $95–110
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- https://www.nytnbus.com
- Adult One-way
- $95–110
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Sebastian to Jacksonville
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Sebastian to West Palm Beach Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- $14–28
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to New York City Chinatown
- Ave. Duration
- 18h 35m
- Frequency
- 5 times a week
- Estimated price
- $160–280
- Schedules at
- flixbus.com
- Phone
- +1 772-343-0217
- Website
- smartshuttleline.com
Shuttle from Melbourne, FL - Mobil Gas to Orlando Airport
- Ave. Duration
- 56 min
- Frequency
- 4 times a day
- Estimated price
- $55–65
- Schedules at
- smartshuttleline.com
- one passenger
- $55–65
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $95–140
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 317+ hotels available in Knoxville.






