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How to get fromPalm Beach to Santeeby plane, car, bus (Flixbus, Greyhound), or train

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There are 7 ways to get from Palm Beach to Santee by plane, car, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly President Donald J. Trump International Airport to Charleston International Airport, drive

    best
    1. Fly from President Donald J. Trump International Airport (PBI) to Charleston International Airport (CHS)plane plane PBI - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    5h
    $124–770

  2. Drive 521.2 mi

    cheapest
    1. Drive from Palm Beach to Santeecar car 521.2 mi
    8h 32m
    $96–138

  3. Bus

    1. Take the bus from West Palm Beach Bus Station to Orlando Bus Stationbus bus FlixBus N2401 / ...
    2. Take the bus from Orlando Bus Station to Orangeburgbus bus FlixBus 2433
    13h 16m
    $168–262

  4. Train, drive (Amtrak)

    1. Take the train from West Palm Beach Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    2. Drive from Charleston Amtrak Station to Santeecar car
    13h 51m
    $202–418

  5. Fly President Donald J. Trump International Airport to Columbia, drive

    1. Fly from President Donald J. Trump International Airport (PBI) to Columbia (CAE)plane plane PBI - CAE
    2. Drive from Columbia-Airport-CAE to Santeecar car
    7h 9m
    $224–1,120

  6. Train to Fort Lauderdale–Hollywood International Airport, fly to Charleston International Airport, drive

    1. Take the train from West Palm Beach to Fort Lauderdaletrain train
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    3. Drive from Charleston-Airport-CHS to Santeecar car
    5h 52m
    $204–1,176

  7. Train to Miami International Airport, fly to Charleston International Airport, drive

    1. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    3. Drive from Charleston-Airport-CHS to Santeecar car
    6h 27m
    $517–1,029

President Donald J. Trump International Airport (PBI) to Charleston International Airport (CHS) flights

Calendar27Weekly Planes
Duration3h 36mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from Palm Beach to Santee.ExpandLaunch map view
  • Distance: 494.2 mi
  • Duration: 5h

What companies run services between Palm Beach, FL, USA and Santee, SC, USA?

You can take a bus from LAKEVIEW AVE at DIXIE HWY to Santee via WPB ITC at BAY J, West Palm Beach Bus Station, Orlando Bus Station, and Orangeburg in around 13h 16m.

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